Pearson S L, Stewart I C, Kellett R J
Edenhall and Eastern General Hospital, Edinburgh.
Scott Med J. 1988 Oct;33(5):343-4. doi: 10.1177/003693308803300516.
Gold compounds have been successfully used for over 50 years in the treatment of rheumatoid arthritis, but their mechanism of action is unknown. The main disadvantage is the frequent occurrence of side effects which often necessitate discontinuation of therapy. Recently, there have been reports of reduction in immunoglobulin levels in patients on gold treatment; we report a further case of hypoglobulinaemia associated with gold therapy and recommend that immunoglobulins be monitored prior to and during treatment.
金化合物已成功用于治疗类风湿性关节炎五十多年，但它们的作用机制尚不清楚。主要缺点是副作用频繁发生，这常常需要中断治疗。最近，有报道称接受金治疗的患者免疫球蛋白水平降低；我们报告了另一例与金疗法相关的低球蛋白血症病例，并建议在治疗前和治疗期间监测免疫球蛋白。
