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国际专家小组关于超声内镜引导下胰腺囊性肿瘤消融的立场声明。

Position statement on EUS-guided ablation of pancreatic cystic neoplasms from an international expert panel.

作者信息

Teoh Anthony Yuen-Bun, Seo Dong Wan, Brugge William, Dewitt John, Kongkam Pradermchai, Linghu Enqiang, Moyer Matthew T, Ryu Ji Kon, Ho Khek Yu

机构信息

Department of Surgery, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong.

Department of Gastroenterology, Asan Medical Centre, Seoul, Korea.

出版信息

Endosc Int Open. 2019 Sep;7(9):E1064-E1077. doi: 10.1055/a-0959-5870. Epub 2019 Aug 29.

DOI:10.1055/a-0959-5870
PMID:31475223
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6715424/
Abstract

Recently, several guidelines with divergent recommendations on management of pancreatic cystic neoplasm have been published but the role of endoscopic ultrasound (EUS)-guided pancreatic cyst ablation has not been thoroughly addressed. The aim of the current paper is to explore the issues surrounding EUS-guided pancreatic cyst ablation by generating a list of clinical questions and providing answers based on best scientific evidence available.  An expert panel in EUS-guided pancreatic cyst ablation was recruited from members of the Asian EUS group and an international expert panel. A list of clinical questions was created and each question allocated to one member to generate a statement in response. The statements were then discussed in three Internet conference meetings between October 2016 and October 2017. The statements were changed until consensus was obtained. Afterwards, the complete set of statements was sent to all the panelist to vote on strength of the statements, classification of the statement sand grading of the evidence.  Twenty-three statements on EUS-guided drainage of pancreatic cyst ablation were formulated. The statements addressed indications for the procedures, technical aspects, pre-procedure and post-procedure management, management of complications, and competency and training in the procedures.  The current set of statements on EUS-guided pancreatic cyst ablation are the first to be published by any endoscopic society. Clinicians interested in developing the technique should reference these statements and future studies should address the key issues raised in the document.

摘要

最近,已发表了几份关于胰腺囊性肿瘤管理的指南,这些指南的建议各不相同,但内镜超声(EUS)引导下的胰腺囊肿消融术的作用尚未得到充分探讨。本文的目的是通过列出一系列临床问题并根据现有最佳科学证据提供答案,来探讨围绕EUS引导下胰腺囊肿消融术的相关问题。 EUS引导下胰腺囊肿消融术专家小组由亚洲EUS小组的成员和一个国际专家小组组成。创建了一系列临床问题,并将每个问题分配给一名成员以生成相应的陈述。然后在2016年10月至2017年10月期间的三次网络会议上对这些陈述进行了讨论。对陈述进行修改,直到达成共识。之后,将完整的陈述集发送给所有小组成员,对陈述的力度、陈述的分类和证据的分级进行投票。 制定了23条关于EUS引导下胰腺囊肿消融术引流的陈述。这些陈述涉及该手术的适应症、技术方面、术前和术后管理、并发症的处理以及该手术的能力和培训。 目前这套关于EUS引导下胰腺囊肿消融术的陈述是首个由任何内镜学会发表的。对开发该技术感兴趣的临床医生应参考这些陈述,未来的研究应解决本文中提出的关键问题。

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本文引用的文献

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European evidence-based guidelines on pancreatic cystic neoplasms.欧洲胰腺囊性肿瘤循证临床实践指南。
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An Evidence-Based Review of Off-Label Uses of Polidocanol.聚多卡醇非适应证使用的循证综述
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Consensus guidelines on the optimal management in interventional EUS procedures: results from the Asian EUS group RAND/UCLA expert panel.共识指南:介入性超声内镜术的最佳管理:来自亚洲超声内镜专家组的 RAND/UCLA 专家小组的结果。
Gut. 2018 Jul;67(7):1209-1228. doi: 10.1136/gutjnl-2017-314341. Epub 2018 Feb 20.
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Technical feasibility, diagnostic yield, and safety of microforceps biopsies during EUS evaluation of pancreatic cystic lesions (with video).超声内镜评估胰腺囊性病变时微活检钳活检的技术可行性、诊断率和安全性(附视频)。
Gastrointest Endosc. 2018 May;87(5):1263-1269. doi: 10.1016/j.gie.2017.12.025. Epub 2018 Jan 6.
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Endoscopic Ultrasound-Guided Pancreatic Cyst Ablation: More Peril Than Promise?内镜超声引导下胰腺囊肿消融术:风险大于前景?
Gastroenterology. 2017 Nov;153(5):1183-1185. doi: 10.1053/j.gastro.2017.09.028. Epub 2017 Oct 4.
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Endoscopy. 2017 Oct;49(10):989-1006. doi: 10.1055/s-0043-119219. Epub 2017 Sep 12.
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