Koch H J, Sedello C, Zinke D
Friedrich-Schiller-Universität, Jena
Allerg Immunol (Leipz). 1988;34(4):261-7.
Factors promoting the phagocytosis of N. gonorrhoeae were estimated in the cervico-vaginal secretions and in serum of 129 female patients suffering from gonorrhea. 76 healthy women served for comparison. The increase of granulocyte-phagocytosis in vitro, mediated by secretions and serum from patients and in part also from patients after therapy was stronger than that of healthy women. Although the absolute amount of phagocytosis mediated by serum was higher, there was clearly a stronger increase of secretion-mediated phagocytosis, while using material from patients. After inactivation of serum and secretions by heating, a decrease of phagocytosis could be observed in patients and healthy women, too. The greater calculated differences in patients than in healthy persons are distinct signs for stronger induction of thermolabile factors in the patients.
对129例淋病女性患者的宫颈阴道分泌物和血清中促进淋病奈瑟菌吞噬作用的因素进行了评估。76名健康女性作为对照。患者分泌物和血清（部分患者治疗后也是如此）介导的体外粒细胞吞噬作用的增强比健康女性更强。虽然血清介导的吞噬作用的绝对量更高，但使用患者材料时，分泌物介导的吞噬作用明显有更强的增强。在通过加热使血清和分泌物失活后，患者和健康女性的吞噬作用也会降低。患者比健康人计算出的差异更大，这是患者中热不稳定因子诱导更强的明显迹象。
