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非消化道头颈部手术后的术后镇痛需求和疼痛感知。

Postoperative Analgesic Requirement and Pain Perceptions after Nonaerodigestive Head and Neck Surgery.

机构信息

Department of Otolaryngology-Head and Neck Surgery, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.

Department of Anesthesiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.

出版信息

Otolaryngol Head Neck Surg. 2019 Dec;161(6):970-977. doi: 10.1177/0194599819871699. Epub 2019 Sep 3.

DOI:10.1177/0194599819871699
PMID:31476960
Abstract

OBJECTIVES

Little data exist on associations between patient factors and postoperative analgesic requirement after head and neck (H&N) surgeries. Such information is important for optimizing postoperative care considering concerns regarding opioid misuse. We analyzed factors associated with narcotic use and pain perception following H&N surgery sparing the upper aerodigestive tract.

STUDY DESIGN

Prospective cohort.

SETTING

Tertiary referral center.

SUBJECTS AND METHODS

From May to October 2017, data were collected for patients undergoing nonaerodigestive H&N procedures requiring hospitalization. Patients completed a preoperative survey querying chronic pain history, narcotic usage, and postoperative pain expectation. Demographics, surgical data, postoperative narcotic use defined by morphine milligram equivalents (MME), pain scores, and Overall Benefit of Analgesia Score (OBAS) were analyzed.

RESULTS

Seventy-six patients, 44 (57.9%) females and 32 (42.1%) males with a mean age of 54.0 years, met inclusion criteria. The most common procedures were parotidectomy (27.6%) and total thyroidectomy (19.7%). Average cumulative 24-hour postoperative MME and calculated MME per hospital day (MME/HD, cumulative MME for hospitalization divided by length of stay) were 40.5 ± 30.6 and 60.8 ± 60.1, respectively. Average pain score throughout the initial 24 hours after surgery was 3.7/10 ± 2.0. Female sex and prior chronic pain diagnosis were associated with higher OBAS after multivariate linear adjustments.

CONCLUSION

Postoperative narcotic requirement in nonaerodigestive H&N surgery is overall low. Female sex and prior chronic pain diagnosis may be associated with higher postoperative OBAS, a validated assessment of pain and opioid-related side effects. This study may serve as a comparison for future studies evaluating narcotic-sparing analgesia and pain perception in nonaerodigestive H&N surgery.

摘要

目的

关于头颈部(H&N)手术后患者因素与术后镇痛需求之间的关联,相关数据较少。考虑到阿片类药物滥用的问题,此类信息对于优化术后护理非常重要。我们分析了与 H&N 手术(不涉及上呼吸道)后使用阿片类药物和疼痛感知相关的因素。

研究设计

前瞻性队列研究。

地点

三级转诊中心。

研究对象和方法

2017 年 5 月至 10 月期间,我们收集了需要住院的非上呼吸道 H&N 手术患者的数据。患者在术前完成了一份调查问卷,询问了慢性疼痛史、阿片类药物使用情况和术后疼痛预期。分析了人口统计学数据、手术数据、术后吗啡毫克当量(MME)定义的阿片类药物使用、疼痛评分和总体镇痛效果评分(OBAS)。

结果

76 名患者符合纳入标准,其中 44 名(57.9%)为女性,32 名(42.1%)为男性,平均年龄为 54.0 岁。最常见的手术为腮腺切除术(27.6%)和甲状腺全切除术(19.7%)。平均 24 小时术后累计 MME 和计算的每住院日 MME(MME/HD,住院期间 MME 总和除以住院天数)分别为 40.5±30.6 和 60.8±60.1。术后最初 24 小时内的平均疼痛评分为 3.7/10±2.0。多变量线性调整后,女性和慢性疼痛诊断史与更高的 OBAS 相关。

结论

非上呼吸道 H&N 手术的术后阿片类药物需求总体较低。女性和慢性疼痛诊断史可能与更高的术后 OBAS 相关,OBAS 是一种评估疼痛和阿片类药物相关副作用的有效方法。本研究可作为未来评估非上呼吸道 H&N 手术中阿片类药物节约性镇痛和疼痛感知的研究的比较。

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