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激光脱毛术后引发的 EMLA 所致高铁血红蛋白血症。

EMLA-induced methemoglobinemia after laser-assisted hair removal procedure.

机构信息

Department of Emergency Medicine, Maimonides Medical Center, Brooklyn, NY, USA.

Department of Emergency Medicine, Maimonides Medical Center, Brooklyn, NY, USA.

出版信息

Am J Emerg Med. 2019 Nov;37(11):2119.e1-2119.e2. doi: 10.1016/j.ajem.2019.158415. Epub 2019 Aug 24.

DOI:10.1016/j.ajem.2019.158415
PMID:31477356
Abstract

This is the case of a 23-year-old female with a past medical history of ADHD and Depression who was evaluated in the emergency department for perioral cyanosis and hypoxia after application of the eutectic mixture of lidocaine and prilocaine (EMLA) local anesthetic prior to a laser-assisted hair removal procedure. This report illustrates a case of methemoglobinemia which is a rare but significant complication of topical anesthetic use.

摘要

这是一位 23 岁女性的病例,她既往有注意力缺陷多动障碍和抑郁症病史,在激光脱毛术前使用了利多卡因和丙胺卡因的低共熔混合物(EMLA)局麻药后,因出现口周发绀和缺氧被收入急诊科评估。本报告说明了一例高铁血红蛋白血症,这是局部麻醉剂使用的罕见但严重的并发症。

相似文献

1
EMLA-induced methemoglobinemia after laser-assisted hair removal procedure.激光脱毛术后引发的 EMLA 所致高铁血红蛋白血症。
Am J Emerg Med. 2019 Nov;37(11):2119.e1-2119.e2. doi: 10.1016/j.ajem.2019.158415. Epub 2019 Aug 24.
2
EMLA-induced methemoglobinemia and systemic topical anesthetic toxicity.复方利多卡因乳膏引起的高铁血红蛋白血症和全身性局部麻醉药毒性。
J Emerg Med. 2004 Jan;26(1):85-8. doi: 10.1016/j.jemermed.2003.03.003.
3
Methemoglobinemia induced by lidocaine-prilocaine cream.利多卡因-丙胺卡因乳膏引起的高铁血红蛋白血症。
Isr Med Assoc J. 2014 Apr;16(4):250-4.
4
[Methemoglobin intoxication by prilocaine in EMLA. Accidental intoxication of an infant with scald injuries].[EMLA中丙胺卡因所致高铁血红蛋白中毒。一名烫伤婴儿的意外中毒]
Anaesthesist. 2009 Apr;58(4):370-4. doi: 10.1007/s00101-009-1512-5.
5
Seizures and Methemoglobinemia After Topical Application of Eutectic Mixture of Lidocaine and Prilocaine on a 3.5-Year-Old Child with Molluscum Contagiosum and Atopic Dermatitis.对一名患有传染性软疣和特应性皮炎的3.5岁儿童局部应用利多卡因和丙胺卡因的共晶混合物后出现癫痫发作和高铁血红蛋白血症。
Pediatr Dermatol. 2016 Sep;33(5):e284-5. doi: 10.1111/pde.12927. Epub 2016 Jul 11.
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[Intoxication with prilocaine/lidocaine can cause serious methemoglobinemia].普里罗卡因/利多卡因中毒可导致严重的高铁血红蛋白血症。
Lakartidningen. 2019 Oct 1;116:FPFT.
7
[Methaemoglobinaemia due to topical administration of local anesthetic for laser depilation].[局部麻醉药用于激光脱毛局部给药导致的高铁血红蛋白血症]
Farm Hosp. 2013 Nov-Dec;37(6):559-61. doi: 10.7399/FH.2013.37.6.969.
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Methemoglobinemia and CNS toxicity after topical application of EMLA to a 4-year-old girl with molluscum contagiosum.对一名患有传染性软疣的4岁女孩局部应用EMLA后出现高铁血红蛋白血症和中枢神经系统毒性。
Pediatr Dermatol. 2006 Nov-Dec;23(6):592-3. doi: 10.1111/j.1525-1470.2006.00319.x.
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[Probable methemoglobinemia following EMLA administration].
An Pediatr (Barc). 2005 Aug;63(2):179-80. doi: 10.1157/13077466.
10
Direct comparison of EMLA versus lidocaine for pain control in Nd:YAG 1,064 nm laser hair removal.在Nd:YAG 1064纳米激光脱毛中,EMLA与利多卡因用于疼痛控制的直接比较。
Dermatol Surg. 2005 Apr;31(4):396-8. doi: 10.1111/j.1524-4725.2005.31104.

引用本文的文献

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Anaphylactic shock secondary to topical EMLA.外用复方利多卡因凝胶引发的过敏性休克。
J Cutan Aesthet Surg. 2025 Apr-Jun;18(2):120-122. doi: 10.4103/JCAS.JCAS_30_23. Epub 2023 Nov 30.
2
Acute Systemic Toxicity Caused by Topical Application of EMLA Cream on a Leg Ulcer: Case Report and Review of Literature.腿部溃疡局部应用EMLA乳膏引起的急性全身毒性:病例报告及文献综述
Dermatol Ther (Heidelb). 2024 Apr;14(4):1057-1062. doi: 10.1007/s13555-024-01139-7. Epub 2024 Apr 3.
3
Acquired Methemoglobinemia in an Infant: Consequence of Prolonged Application of Eutectic Mixture of Local Anesthetics (EMLA) Cream for Spontaneous Abscess Drainage.
婴儿获得性高铁血红蛋白血症:局部麻醉剂(EMLA)乳膏长期用于自发脓肿引流的后果。
Cureus. 2022 Nov 9;14(11):e31304. doi: 10.7759/cureus.31304. eCollection 2022 Nov.
4
Benzocaine-induced methaemoglobinaemia in an adolescent with sepsis.苯佐卡因致脓毒症青少年亚甲蓝血症。
BMJ Case Rep. 2022 Feb 28;15(2):e248013. doi: 10.1136/bcr-2021-248013.