Kashimoto Kimiaki, Asai Katsunori, Kinoshita Manabu, Okita Yoshiko, Tanabe Shogo, Yamane Yasuhiko, Kawamata Minoru, Yoneda Akitoshi, Nakanishi Katsuyuki
Department of Diagnostic and Interventional Radiology, Osaka International Cancer Institute, Japan.
Department of Neurosurgery, Osaka International Cancer Institute, Japan.
Neuroradiol J. 2019 Dec;32(6):452-457. doi: 10.1177/1971400919873894. Epub 2019 Sep 3.
The most appropriate imaging protocol for three-dimensional rotational venography (3D RV) has not been established. The aim of this study was to optimise the protocol for 3D RV with low-dose contrast media using time-density curve analysis.
Twenty-five consecutive patients with brain tumours who received preoperative assessment with 3D RV were retrospectively collected and included in this study. To optimise the imaging delay time of 3D RV with low-dose contrast media, time-density curve analysis was performed on two-dimensional conventional angiography. The image quality for depicting cortical veins and venous sinuses was compared to that of magnetic resonance (MR) venography in five cases.
A total of 27 3D RVs were performed in 25 patients. The time-density curves of cortical veins were different from those of cerebral arteries or sinuses. The mean time to peak of cortical veins was significantly longer than the time to peak of cerebral arteries (2.47 ± 0.35 seconds vs. 6.44 ± 1.14 seconds; < 0.0001) and shorter than the time to peak of venous sinuses (6.44 ± 1.14 seconds vs. 8.18 ± 1.12 seconds; < 0.0001). The optimal imaging delay time could be determined as the phases in which cortical arterial opacities disappeared and cortical veins started to appear. The mean dose of injected contrast media was 5.3 mL. The image quality of cortical veins in 3D RV was superior to that in MR venography in all cases.
Three-dimensional RV with low-dose contrast media was useful for the preoperative assessment of cortical veins in patients with brain tumours.
三维旋转静脉造影（3D RV）最适宜的成像方案尚未确立。本研究的目的是通过时间-密度曲线分析优化低剂量造影剂下3D RV的方案。
回顾性收集连续25例接受3D RV术前评估的脑肿瘤患者并纳入本研究。为优化低剂量造影剂下3D RV的成像延迟时间，对二维传统血管造影进行时间-密度曲线分析。将5例患者皮质静脉和静脉窦的成像质量与磁共振（MR）静脉造影的成像质量进行比较。
25例患者共进行了27次3D RV检查。皮质静脉的时间-密度曲线与脑动脉或静脉窦的不同。皮质静脉的平均峰值时间明显长于脑动脉的峰值时间（2.47±0.35秒对6.44±1.14秒；<0.0001）且短于静脉窦的峰值时间（6.44±1.14秒对8.18±1.12秒；<0.0001）。最佳成像延迟时间可确定为皮质动脉显影消失且皮质静脉开始显影的时期。注入造影剂的平均剂量为5.3 mL。在所有病例中，3D RV中皮质静脉的成像质量均优于MR静脉造影。
低剂量造影剂的三维RV对脑肿瘤患者皮质静脉的术前评估有用。
