Tonouhewa A B N, Amagbégnon R, Atchadé S P, Hamidović A, Mercier A, Dambrun M, Migot-Nabias F, Savi de Tové Y Sissinto, Sahibi H, Laboudi M, Sahidou S, Dardé M-L, Kindé-Gazard D, Farougou S
Unité de recherche sur les maladies transmissibles (URMAT), université d'Abomey-Calavi, 01 BP 2009, Cotonou, Bénin.
Laboratoire de recherche en biologie appliquée (LARBA), université d'Abomey-Calavi, 01 BP 2009, Cotonou, Bénin.
Bull Soc Pathol Exot. 2019;112(2):79-89. doi: 10.3166/bspe-2019-0078.
To assess the seroprevalence of toxoplasmosis among pregnant women in Benin, we conducted a meta-analysis using the PRISMA criteria. Al research published between 1990 and 2018 on toxoplasmosis among pregnant women Benin were eligible. A total of five databases were investigated, and the extracted data were subjected to a meta-analysis under R 3.1 using both random effect model and fixed effect model. The overall prevalence of toxoplasma-specific IgG among pregnant women was 47% (CI 95%: 40-53) and that of specific IgM was 2% (CI 95%: 1-3). The infection rate in urban areas (52%) was significantly higher than in rural areas (33%). The two main risk factors identified by the various eligible studies were the age of the pregnant women and the consumption of raw vegetables. We show that toxoplasmosis is endemic in pregnant women in Benin, implying that primary prevention measures must be put in place by the competent authorities to control this infection.
为评估贝宁孕妇弓形虫病的血清流行率，我们采用PRISMA标准进行了一项荟萃分析。1990年至2018年间发表的所有关于贝宁孕妇弓形虫病的研究均符合条件。共调查了五个数据库，并在R 3.1下使用随机效应模型和固定效应模型对提取的数据进行荟萃分析。孕妇中弓形虫特异性IgG的总体流行率为47%（95%置信区间：40 - 53），特异性IgM的总体流行率为2%（95%置信区间：1 - 3）。城市地区的感染率（52%）显著高于农村地区（33%）。各项符合条件的研究确定的两个主要风险因素是孕妇年龄和生食蔬菜的习惯。我们发现弓形虫病在贝宁孕妇中呈地方性流行，这意味着主管当局必须采取一级预防措施来控制这种感染。
