Bailey Christopher, Meyer Jessica, Briskin Susannah, Tangen Christopher, Hoffer S Alan, Dundr Jason, Brennan Bethany, Smith Paul
Departments of Neurology (Drs Bailey and Meyer), Pediatrics (Dr Briskin), Medicine (Dr Tangen), Neurosurgery (Dr Hoffer), and Rehabilitation Services (Messrs Dundr and Smith and Dr Brennan), University Hospitals Cleveland Medical Center, Cleveland, Ohio; and School of Medicine, Case Western Reserve University, Cleveland, Ohio (Drs Bailey, Meyer, Briskin, and Hoffer).
J Head Trauma Rehabil. 2019 Nov/Dec;34(6):375-384. doi: 10.1097/HTR.0000000000000527.
To describe a model of multidisciplinary concussion management and explore management methods in the acute and post-acute settings.
A multidisciplinary concussion management program within a large health system.
Patients with sports and non-sports-related concussions aged 14 to 18 years with persisting concussion symptoms at 4 weeks postinjury or beyond.
Pilot randomized controlled trial comparing a subsymptom threshold exercise program with standard-of-care treatment in the post-acute setting.
Beck Depression Inventory-II and the Post-Concussion Scale-Revised.
Across groups, 60% improvement in concussion symptoms was noted. After removing the influence of depression, the intervention showed a large effect on symptom reduction, with participants in the intervention group improving more than those in the control group. There was no difference in response to the intervention by the sports and nonsports groups.
Results demonstrate that exercise intervention is effective in reducing symptoms in adolescents with persisting symptoms. The finding that participants in the control group who underwent education, light activity, and sophisticated monitoring still had meaningful recovery supports the utility of active engagement in a multidisciplinary management program. Finally, depression had a clinically meaningful effect on recovery, highlighting the need for targeted intervention of noninjury factors relevant to persisting symptoms.
描述多学科脑震荡管理模型,并探索急性和急性后期的管理方法。
大型医疗系统内的多学科脑震荡管理项目。
14至18岁的运动和非运动相关脑震荡患者,受伤后4周或更长时间仍有持续的脑震荡症状。
在急性后期进行的试点随机对照试验,比较亚症状阈值运动计划与标准护理治疗。
贝克抑郁量表第二版和修订后的脑震荡后量表。
各组脑震荡症状均有60%的改善。去除抑郁影响后,干预对症状减轻有显著效果,干预组参与者的改善程度高于对照组。运动组和非运动组对干预的反应无差异。
结果表明,运动干预对持续有症状的青少年减轻症状有效。接受教育、轻度活动和精密监测的对照组参与者仍有显著恢复,这一发现支持了积极参与多学科管理项目的作用。最后,抑郁对恢复有临床显著影响,突出了对与持续症状相关的非损伤因素进行针对性干预的必要性。