Chimerix, Inc., Durham, North Carolina; and.
Communications, Advanced Accelerator Applications, USA, Inc., Millburn, New Jersey
J Nucl Med. 2019 Sep;60(Suppl 2):20S-24S. doi: 10.2967/jnumed.118.220798.
Until recently, it has been challenging to engage Wall Street and large pharmaceutical companies in radiopharmaceutical opportunities. The modest economic prospects of most diagnostic radiopharmaceuticals have not attracted keen interest from the broader business community, despite the rapid advancement of diagnostic imaging capabilities and their increasingly crucial role in the therapeutic process. Similarly, compelling science supporting select radiopharmaceutical therapies in oncology has been overshadowed by the unique challenges posed by this class of drugs and historical commercial failures that serve as sobering reminders of risk. Fortunately, a few notable successes in the targeted radioligand therapeutic space are changing this dynamic, fueling a new flow of investor capital into these technologies and inciting increased merger and acquisition activity that has yielded significant value creation for investors. If the nuclear medicine industry is able to continue to effectively manage historical challenges, then there is significant opportunity for a new and promising wave of radioligand therapies to significantly change the oncology treatment paradigm and elevate the profile of the entire nuclear medicine sector.
直到最近,让华尔街和大型制药公司参与放射性药物的机会一直具有挑战性。尽管诊断成像能力的快速发展及其在治疗过程中日益重要的作用,但大多数诊断放射性药物的适度经济前景并未引起更广泛商业界的浓厚兴趣。同样,支持肿瘤学中某些放射性药物治疗的令人信服的科学也因这类药物所带来的独特挑战以及历史上商业失败而黯然失色,这些失败提醒人们注意风险。幸运的是,靶向放射性配体治疗领域的一些显著成功正在改变这种动态,为这些技术注入了新的投资者资金,并引发了更多的并购活动,为投资者创造了巨大的价值。如果核医学行业能够继续有效地应对历史挑战,那么放射性配体疗法的新一轮有前途的浪潮将有很大机会显著改变肿瘤学治疗模式,并提升整个核医学领域的形象。