Joint Shantou International Eye Center, Shantou University & the Chinese University of Hong Kong, Shantou, China.
Department of Ophthalmology and Vision Sciences, Chinese University of Hong Kong, Hong Kong, China.
Sci Rep. 2019 Sep 3;9(1):12678. doi: 10.1038/s41598-019-49117-w.
The purpose of this study is to evaluate the prognostic factors associated with visual outcomes in the salvageable eyes with posttraumatic endophthalmitis. We retrospectively reviewed the medical records of all patients diagnosed with posttraumatic endophthalmitis in our hospital between 2008 and 2015. The following information was collected: age, sex, etiology, past medical history, clinical manifestations, wound location, microbiology, blood leukocyte counts, types of interventions, initial visual acuities and final visual acuities. Univariate and multivariate analyses were used to explore the factors associated with final best-corrected visual acuity. In total, 98 eyes of 98 patients were included in our study. Fifty-seven eyes underwent vitrectomy, 27 of them had silicone oil tamponade, 38 eyes received intravitreal ceftazidime only and 3 eyes received intracameral ceftazidime. In univariate analysis, poor initial visual acuity, presence of intraocular foreign body, number of intravitreal injections, retinal detachment and Zone 3 injury were associated with poor visual outcome. In multivariable analysis, poor initial visual acuity, presence of intraocular foreign body and number of intravitreal injections were independently associated with poor visual outcome. The silicone oil group had fewer repeated intravitreal injections than the group without oil tamponade. We concluded that the visual outcome of salvageable eyes with posttraumatic endophthalmitis is associated with initial visual acuity, presence of intraocular foreign body and number of intravitreal antibiotic injections.
本研究旨在评估与外伤性眼内炎可挽救眼视力结局相关的预后因素。我们回顾性分析了 2008 年至 2015 年期间我院外伤性眼内炎患者的病历资料。收集了以下信息：年龄、性别、病因、既往病史、临床表现、伤口位置、微生物学、白细胞计数、干预类型、初始视力和最终视力。使用单因素和多因素分析来探讨与最终最佳矫正视力相关的因素。共有 98 例 98 只眼纳入本研究。57 只眼行玻璃体切除术，其中 27 只眼硅油填充，38 只眼仅玻璃体腔注射头孢他啶，3 只眼前房内注射头孢他啶。单因素分析显示，初始视力差、眼内异物、玻璃体腔注射次数、视网膜脱离和 3 区损伤与视力不良结局相关。多因素分析显示，初始视力差、眼内异物和玻璃体腔注射次数与视力不良结局独立相关。硅油组重复玻璃体腔注射次数少于无硅油填充组。我们得出结论，外伤性眼内炎可挽救眼的视力结局与初始视力、眼内异物和玻璃体腔抗生素注射次数有关。
