Park Joong Hyun, Kim Dong Yoon, Ha Ahnul, Ma Dae Joong, Lee Hye Jin, Jeong Jinho, Kim Jin Young
Department of Ophthalmology, Jeju National University Hospital, Jeju National University School of Medicine, Jeju, Republic of Korea.
Department of Ophthalmology, Chungbuk National University Hospital, Chungbuk National University College of Medicine, Cheongju, Republic of Korea.
J Ophthalmol. 2021 Mar 2;2021:6620926. doi: 10.1155/2021/6620926. eCollection 2021.
To analyze the microbiological causes of infectious endophthalmitis on an isolated island over ten years.
A retrospective review of the medical records of 49 eyes clinically diagnosed with infectious endophthalmitis between January 2009 and December 2018 was done. The subjects were recruited from a single tertiary referral center on Jeju Island. The baseline characteristics of all subjects were investigated, and a culture examination was performed. The isolated pathogens were analyzed to determine how their microbiological features differed from those in regions with different geographical conditions.
Of the 49 eyes, causative microorganisms were identified in 27 eyes (55.1%). Bacteria were found in 24 cases and fungi in 3 cases. Among the exogenous causes, species () were the most common pathogens (7 cases). was the second most common causative pathogen (4 cases) followed by species (3 cases). The most frequent endogenous origin was due to (6 cases). The subjects were divided into two groups according to the treatment results and analyzed for predisposing factors related to visual outcomes. The presence of diabetes mellitus ( = 0.038) and initial visual acuity ( ≤ 0.001) were significant predisposing factors for visual outcomes.
The causative microorganisms of endogenous endophthalmitis on Jeju Island were not different from those reported previously. However, isolated exogenous microorganisms were different from those reported in other studies from inland areas. A high incidence and atypical clinical features of and in exogenous endophthalmitis were observed, reflective of the distinct climatic features of Jeju Island: high humidity and temperature. Therefore, considering the causative microorganisms of exogenous endophthalmitis, it may be assumed that the causative microorganisms of exogenous endophthalmitis and its clinical manifestations differ according to the region.
分析一个孤立岛屿上十年来感染性眼内炎的微生物学病因。
对2009年1月至2018年12月期间临床诊断为感染性眼内炎的49只眼的病历进行回顾性研究。研究对象来自济州岛的一家单一的三级转诊中心。调查了所有研究对象的基线特征，并进行了培养检查。对分离出的病原体进行分析，以确定其微生物学特征与不同地理条件地区的病原体有何不同。
49只眼中，27只眼（55.1%）鉴定出致病微生物。24例发现细菌，3例发现真菌。在外源性病因中， 种（）是最常见的病原体（7例）。 是第二常见的致病病原体（4例），其次是 种（3例）。最常见的内源性病因是由于 （6例）。根据治疗结果将研究对象分为两组，并分析与视力预后相关的易感因素。糖尿病的存在（=0.038）和初始视力（≤0.001）是视力预后的重要易感因素。
济州岛感染性眼内炎的致病微生物与先前报道的没有差异。然而，分离出的外源性微生物与内陆地区其他研究报道的不同。在外源性眼内炎中观察到 和 的高发病率和非典型临床特征，这反映了济州岛独特的气候特征：高湿度和高温。因此，考虑到外源性眼内炎的致病微生物，可以假设外源性眼内炎的致病微生物及其临床表现因地区而异。
