Bhartiya Manish, Hans Bandhul, Sundaray Sambit, Sagar Amitabh
Neurology, All India Institute of Medical Sciences, New Delhi, IND.
Forensic Medicine, All India Institute of Medical Sciences, New Delhi, IND.
Cureus. 2019 Aug 20;11(8):e5438. doi: 10.7759/cureus.5438.
Amitraz is a widely used insecticide and antiparasitic drug. It can cause poisoning in humans via oral, inhalation, and dermal routes. Clinical features hence produced may mimic organophosphate (OP) poisoning because of several shared features (miosis, bradycardia, hypotension) along with a history of possible insecticide poisoning. But the presence of hyperglycemia, hypothermia, and reduced gastrointestinal motility along with normal serum cholinesterase levels and the absence of fasciculations and a hypersecretory state (salivation, lacrimation, perspiration, and diarrhea) point against OP poisoning. Analysis of the poison container also helps confirm the poison. Management is mostly supportive with a good prognosis.
双甲脒是一种广泛使用的杀虫剂和抗寄生虫药物。它可通过口服、吸入和皮肤途径导致人体中毒。由于存在一些共同特征（瞳孔缩小、心动过缓、低血压）以及可能的杀虫剂中毒史，由此产生的临床特征可能类似于有机磷（OP）中毒。但高血糖、体温过低和胃肠蠕动减弱，以及血清胆碱酯酶水平正常，且不存在肌束震颤和分泌亢进状态（流涎、流泪、出汗和腹泻），这些都不支持OP中毒。对毒物容器的分析也有助于确认毒物。治疗主要是支持性的，预后良好。
