Wang Dong Liang, Song Hai Dong, Xu Ke, Liu Ruen
Department of Neurosurgery,Peking University People's Hospital,Beijing 100044,China.
Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2019 Aug 30;41(4):566-571. doi: 10.3881/j.issn.1000-503X.11500.
Epilepsy has high incidence and complex etiologies,and its treatment remains challenging.For around 70% of people with epilepsy,seizures can be controlled after proper antiepileptic treatment.The availability of some new antiepileptic drugs in recent years has offered new options for epileptic patients.A solid knowledge on the pharmacokinetics,efficacy,and tolerability profiles of these new antiepileptic drugs will help to provide safe,proper,reasonable,and standardized treatment for patients.
癫痫发病率高且病因复杂,其治疗仍然具有挑战性。对于大约70%的癫痫患者,经过适当的抗癫痫治疗后癫痫发作可以得到控制。近年来一些新型抗癫痫药物的出现为癫痫患者提供了新的选择。扎实掌握这些新型抗癫痫药物的药代动力学、疗效和耐受性特征,将有助于为患者提供安全、恰当、合理和规范的治疗。