类二十烷酸与皮肤。
Eicosanoids and skin.
作者信息
De Nucci G
机构信息
William Harvey Research Institute, St Bartholomew's Hospital Medical College, London, U.K.
出版信息
Biochem Soc Trans. 1988 Oct;16(5):680-2. doi: 10.1042/bst0160680.
PMID:3148484
Abstract
A better understanding of the physiological and pathological roles of lipoxygenase metabolites on skin will be obtained with the development of safe and specific 5- and 12-lipoxygenase inhibitors. Lipocortins have been cloned and the results of clinical trials with them should provide further insight into the mechanism(s) of action of steroids on skin diseases.
摘要
随着安全且特异的5-脂氧合酶和12-脂氧合酶抑制剂的研发，人们将对脂氧合酶代谢产物在皮肤中的生理和病理作用有更深入的了解。脂皮质素已被克隆，针对它们的临床试验结果应能为类固醇治疗皮肤病的作用机制提供进一步的见解。
Zotero 插件