Sekine Mai, Masutani Satoshi, Imamura Tomohiko, Iwamoto Yoichi, Muraji Shota, Yoshiba Shigeki, Ishido Hirotaka, Sumitomo Naokata
Department of Pediatrics, Saitama Medical Center, Saitama Medical University.
Department of Pediatric Cardiology, Saitama Medical University International Medical Center.
Int Heart J. 2019 Sep 27;60(5):1201-1205. doi: 10.1536/ihj.18-723. Epub 2019 Sep 4.
Right-sided accessary pathways in patients with Wolff-Parkinson-White (WPW) syndrome may cause cardiac dyssynchrony and dilated cardiomyopathy, with a characteristic septal shape, irrespective of any supraventricular tachycardia episodes. We report on two infants (13 and 5 months), whose right-sided accessary pathway-induced dilated cardiomyopathy was successfully treated by flecainide for the first time. After the flecainide administration, an abnormal aneurysmal dilation of the basal interventricular septum was almost restored to normal, and the decreased ejection fraction recovered. Flecainide use may be an important therapeutic option for this entity to avoid catheter ablation during infancy.
Wolff-Parkinson-White（WPW）综合征患者的右侧附加通路可能导致心脏不同步和扩张型心肌病，具有特征性的间隔形状，无论是否有室上性心动过速发作。我们报告了两名婴儿（分别为13个月和5个月），其右侧附加通路引起的扩张型心肌病首次通过氟卡尼成功治疗。给予氟卡尼后，基底室间隔的异常动脉瘤样扩张几乎恢复正常，射血分数下降得到恢复。对于该疾病，使用氟卡尼可能是一种重要的治疗选择，以避免在婴儿期进行导管消融。
