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后多次失败的骨盆骨折尿道损伤修复术后 RE 再行尿道成形术。

RE Re Do urethroplasty after multiple failed surgeries of pelvic fracture urethral injury.

机构信息

Kulkarni Reconstructive Urology Center, 3, Rajpath Society, Opp Vanaz Engineering, Paud Road, Pune, 411038, India.

出版信息

World J Urol. 2020 Dec;38(12):3019-3025. doi: 10.1007/s00345-019-02917-1. Epub 2019 Sep 4.

Abstract

INTRODUCTION

We quantify surgical success rate in the management of pelvic fracture urethral injury (PFUI) with repeat urethroplasty in the setting of two or more failed prior urethroplasties.

MATERIALS AND MATERIALS

A retrospective analysis was completed of a single surgeon urethroplasty database from Jan 1, 2012 to June 31, 2018. Patients with a history of PFUI recurrent urethral stricture despite two or more failed prior urethroplasty procedures were included.

RESULTS

We identified 87 patients that had two more more failed prior urethroplasties. These had 2 main categories. One requiring anastomotic urethroplasty and other requiring substitution urethroplasty. Total success rate was 74.75% for anastomotic group and 84.61% for substitution group with a median follow-up of 34 months (range 6-60). Overall success rate for re redo Urethroplasty was 82.70%. Bulbar urethral ischemic necrosis was identified in 14 of 64 patients (21.9%). In these cases urethral substitution measures were performed including 12 with preputial flap and tubularization, 1 sigmoid colon substitution, medial thigh flap. No significant difference was observed between the success or failure group with respect to age, BMI, stricture length, number of prior urethroplasty procedure or endoscopic procedures or comorbidities.

CONCLUSIONS

Our findings demonstrate that high success rates can be achieved for repeat urethroplasty in recurrent PFUI urethral stricture after two or more failed prior urethroplasty procedures. Bulbar urethral ischemic necrosis is a common finding in this patient population. Patients should be managed at a tertiary high volume referral center.

摘要

介绍

我们在两次或更多次先前尿道成形术失败的情况下,通过重复尿道成形术来量化骨盆骨折后尿道损伤(PFUI)的手术成功率。

材料和方法

对 2012 年 1 月 1 日至 2018 年 6 月 31 日期间一位外科医生的尿道成形术数据库进行了回顾性分析。包括有 PFUI 复发性尿道狭窄病史且尽管进行了两次或更多次先前失败的尿道成形术的患者。

结果

我们确定了 87 例有两次或更多次先前尿道成形术失败的患者。这些患者有 2 个主要类别。一个需要吻合尿道成形术,另一个需要替代尿道成形术。吻合组的总成功率为 74.75%,替代组为 84.61%,中位随访时间为 34 个月(范围 6-60)。再次尿道成形术的总成功率为 82.70%。64 例患者中有 14 例(21.9%)发生球部尿道缺血性坏死。在这些情况下,采用了尿道替代措施,包括 12 例采用包皮瓣和管状化、1 例采用乙状结肠替代、1 例采用大腿内侧皮瓣。在成功或失败组之间,年龄、BMI、狭窄长度、先前尿道成形术次数或内镜检查次数或合并症方面无显著差异。

结论

我们的研究结果表明,在两次或更多次先前尿道成形术失败后,对于复发性 PFUI 尿道狭窄,重复尿道成形术可以获得较高的成功率。球部尿道缺血性坏死是该患者群体的常见表现。患者应在三级高容量转诊中心进行治疗。

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