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妊娠期间大量咯血需静脉-静脉体外膜肺氧合治疗的病例报告。

Case report of massive hemoptysis in pregnancy requiring veno-venous extracorporeal membrane oxygenation.

作者信息

Stiff Alyssa, Harrison Rachel, Palatnik Anna

机构信息

Department of Obstetrics and Gynecology, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.

出版信息

J Obstet Gynaecol Res. 2019 Dec;45(12):2452-2455. doi: 10.1111/jog.14110. Epub 2019 Sep 4.

DOI:10.1111/jog.14110
PMID:31486147
Abstract

Hemoptysis in pregnancy is rare and can be life-threatening. This case describes management of hemoptysis in pregnancy requiring veno-venous extracorporeal membrane oxygenation (VV-ECMO). The patient presented with massive hemoptysis in respiratory failure at 26 weeks gestation. VV-ECMO was utilized for maternal stability due to severe hypoxia from lung parenchymal damage. An extensive work-up for hemoptysis returned negative except for an elevated Bordetella pertussis IgG antibody. The patient was delivered via cesarean section with a complicated post-partum course. She and the infant were discharged in stable condition after long hospital stays. Prior publications describing VV-ECMO use in pregnancy are limited to treatment of respiratory infections such as influenza or pneumonia. This case is the first in the literature to describe VV-ECMO utilization for hemoptysis in pregnancy, specifically, and demonstrates its significant benefit in cases of respiratory failure due to hemoptysis.

摘要

孕期咯血较为罕见且可能危及生命。本病例描述了一名孕期咯血患者的治疗过程,该患者需要静脉-静脉体外膜肺氧合(VV-ECMO)支持。患者在妊娠26周时因呼吸衰竭出现大量咯血。由于肺实质损伤导致严重缺氧,VV-ECMO被用于维持母体稳定。除百日咳博德特氏菌IgG抗体升高外,针对咯血的全面检查结果均为阴性。患者通过剖宫产分娩,产后病程复杂。经过长时间住院治疗后,她和婴儿均康复出院。此前关于孕期使用VV-ECMO的文献报道仅限于治疗流感或肺炎等呼吸道感染。本病例是文献中首例专门描述孕期咯血使用VV-ECMO的案例,并证明了其在咯血导致呼吸衰竭病例中的显著益处。

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引用本文的文献

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Massive hemoptysis in pregnancy treated by ECMO combined with electronic bronchoscopy: A case report.体外膜肺氧合联合电子支气管镜治疗妊娠合并大量咯血:一例报告
Heliyon. 2023 Dec 14;10(1):e23702. doi: 10.1016/j.heliyon.2023.e23702. eCollection 2024 Jan 15.
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Management of life-threatening malignant central airway obstruction: A novel approach of using extracorporeal membrane oxygenation with tumor debulking and stenting.危及生命的恶性中央气道梗阻的管理:一种采用体外膜肺氧合联合肿瘤减瘤及支架置入的新方法。
Respir Med Case Rep. 2022 Jul 31;39:101718. doi: 10.1016/j.rmcr.2022.101718. eCollection 2022.
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Venovenous Extracorporeal Membrane Oxygenation Combined with Fiberoptic Bronchoscopy-Assisted CO Cryotherapy in the Treatment of Massive Hemoptysis in Pregnancy: A Case Report.
静脉-静脉体外膜肺氧合联合纤维支气管镜辅助CO冷冻治疗妊娠合并大量咯血:1例报告
Int J Gen Med. 2020 Nov 27;13:1291-1296. doi: 10.2147/IJGM.S287666. eCollection 2020.