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以患者为中心而非以疾病为中心:对指南和多病共存的综述。

Patient-centred and not disease-focused: a review of guidelines and multimorbidity.

机构信息

Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore.

Clinical Research Unit, National Healthcare Group Polyclinics, Singapore.

出版信息

Singapore Med J. 2020 Nov;61(11):584-590. doi: 10.11622/smedj.2019109. Epub 2019 Sep 6.

Abstract

INTRODUCTION

Single-disease clinical practice guidelines (CPGs) are not designed to consider patients with multiple chronic conditions, or multimorbidity. Applying multiple CPGs to a single patient may create an overwhelming treatment burden resulting in poor adherence and clinical outcomes. No studies on the cumulative treatment burden from multiple CPGs have been done in Singapore. We described the treatment burden on a hypothetical patient with six chronic conditions when multiple CPGs were applied, and appraised each CPG with respect to the patient-centred care of older adults with multimorbidity.

METHODS

A treatment plan was developed for a hypothetical 72-year-old woman with asthma, depression, diabetes mellitus, dyslipidaemia, hypertension and osteoarthritis according to the latest CPG recommendations. Treatment burden was quantified in terms of time spent, cost, and the number of appointments and medications. Each CPG was appraised with respect to the care of older adults, patients with multimorbidity and patient-centred care.

RESULTS

Following the CPGs strictly, an average of about two hours was spent daily taking 14 different medications and following 21 non-pharmacological recommendations. Her out-of-pocket payment was SGD 104.42 monthly despite a near 90% subsidy on healthcare bills. Patient-centred care of older adults with multimorbidity was inadequately addressed in all six CPGs.

CONCLUSION

When six CPGs were cumulatively followed, the treatment burden was time-consuming, costly and disruptive. Patients' goals and preferences must guide prioritisation of care such that treatment burden remains minimally disruptive to their lives. Developing future CPGs to deliver patient-centred rather than disease-focused care will be crucial to the management of multimorbidity.

摘要

简介

单病种临床实践指南(CPGs)并非专为考虑患有多种慢性疾病或多种合并症的患者而设计。将多个 CPG 应用于单个患者可能会带来巨大的治疗负担,导致患者无法坚持治疗,临床效果不佳。新加坡尚未开展过关于多个 CPG 累积治疗负担的研究。我们描述了在对一位患有六种慢性疾病的假设患者应用多个 CPG 时的治疗负担,并评估了每个 CPG 在多合并症老年患者的以患者为中心的护理方面的表现。

方法

根据最新的 CPG 建议,为一位 72 岁患有哮喘、抑郁症、糖尿病、血脂异常、高血压和骨关节炎的假设女性制定了治疗计划。以时间、成本、就诊次数和药物数量来衡量治疗负担。根据对老年患者、多合并症患者和以患者为中心的护理的关怀程度,评估每个 CPG。

结果

严格遵循 CPG 会导致患者每天花费约两小时服用 14 种不同的药物,并遵循 21 种非药物建议。尽管医疗费用近 90%得到补贴,但她的自付费用仍为每月 104.42 新加坡元。所有六个 CPG 都未能充分考虑多合并症老年患者的以患者为中心的护理。

结论

当累积遵循六个 CPG 时,治疗负担既耗时、昂贵又具干扰性。患者的目标和偏好必须指导护理的优先级,以将治疗负担对其生活的干扰降至最低。制定未来以患者为中心而不是以疾病为中心的 CPG 将是多合并症管理的关键。

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