Department of Environmental Engineering, Faculty of Chemical and Food Technology, Slovak University of Technology in Bratislava, Radlinského 9, 812 37, Bratislava, Slovak Republic.
Department of Organic Technology, Faculty of Chemical and Food Technology, Slovak University of Technology in Bratislava, Radlinského 9, 812 37, Bratislava, Slovak Republic.
Environ Sci Pollut Res Int. 2019 Nov;26(31):31846-31855. doi: 10.1007/s11356-019-06314-4. Epub 2019 Sep 5.
The presented study summarizes laboratory tests results to define the inhibition effect of selected pharmaceuticals on biogas production under anaerobic digestion conditions. Two sets of inhibition tests were realized: (i) with real anaerobic sludge (from municipal wastewater treatment plant (WWTP) where sludge is present and includes a wide spectrum of pharmaceuticals over a long period) and (ii) with laboratory sludge (sludge without pharmaceuticals). Methanogenic tests lasting 20 days were performed with three analgesics (diclofenac, ibuprofen, and tramadol), two antibiotics (amoxicillin and ciprofloxacin), β-blocker (atenolol), three psychoactive compounds (carbamazepine, caffeine, and cotinine), and a mixture of these compounds. All tests were performed with two concentrations of pharmaceuticals (10 μg/L and 500 μg/L). Results of the methanogenic tests showed the different behaviors of the investigated sludges in the presence of individual pharmaceuticals. Stimulation of anaerobic digestion was mostly detected for laboratory (unadapted) sludge (e.g., the addition of ibuprofen at a concentration of 500 μg/L increased biogas production by 61%). On the other hand, pharmaceuticals inhibited biogas production for real sludge (e.g., the addition of ciprofloxacin 500 μg/L decreased biogas production by 52%).
本研究总结了实验室测试结果，以确定在厌氧消化条件下，选定药物对沼气生成的抑制作用。进行了两组抑制测试：(i) 使用实际的厌氧污泥（来自城市污水处理厂（WWTP），其中存在污泥，并且在很长一段时间内包含广泛的药物）和 (ii) 使用实验室污泥（不含药物的污泥）。进行了为期 20 天的产甲烷测试，使用了三种镇痛药（双氯芬酸、布洛芬和曲马多）、两种抗生素（阿莫西林和环丙沙星）、β-受体阻滞剂（阿替洛尔）、三种精神活性化合物（卡马西平、咖啡因和可替宁）以及这些化合物的混合物。所有测试均使用两种药物浓度（10 μg/L 和 500 μg/L）进行。产甲烷测试的结果表明，在所研究的污泥中，不同的药物表现出不同的行为。实验室（未适应）污泥中大多检测到厌氧消化的刺激（例如，在 500 μg/L 的浓度下添加布洛芬可使沼气产量增加 61%）。另一方面，药物抑制了实际污泥的沼气生成（例如，添加 500 μg/L 的环丙沙星可使沼气产量减少 52%）。
