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优化门诊妇科泌尿手术围手术期疼痛控制。

Optimizing Perioperative Pain Control After Ambulatory Urogynecologic Surgery.

机构信息

University of Massachusetts Medical Center, Wooster, MA.

Department of Obstetrics and Gynecology, Beth Israel Deaconess Medical Center Boston, MA.

出版信息

Female Pelvic Med Reconstr Surg. 2020 Aug;26(8):483-487. doi: 10.1097/SPV.0000000000000775.

Abstract

OBJECTIVES

The objective of this study was to determine the impact of a multimodal protocol on opiate use and postoperative pain after ambulatory urogynecologic surgery.

METHODS

This was a retrospective cohort study comparing ambulatory urogynecologic surgery patients treated under a standard perioperative pain protocol with those treated under a multimodal perioperative pain protocol. The multimodal protocol consisted of preoperative gabapentin and acetaminophen and postoperative scheduled doses of acetaminophen and nonsteroidal anti-inflammatory drugs. Pain scores were obtained from nursing records and assessed on the Numeric Rating Scale 11 per hospital protocol. All opioid dosages were converted into morphine milligram equivalents using standardized conversion tables.

RESULTS

We treated 109 patients under the standard protocol and 112 under the multimodal protocol. Patients had similar baseline characteristics. Overall, a minority of patients (39%) used postoperative opioids; this was similar in the 2 groups (P=0.45). The 2 groups also were similar with regard to the total postoperative morphine milligram equivalents (P=0.35). Postoperatively, patients treated under the standard protocol had higher mean pain scores (2.2 vs 1.4, P=0.002). Patients treated under the standard protocol were also significantly more likely to report postoperative pain (69%) than those treated under the multimodal protocol (52%; P=0.01), and the multimodal protocol was associated with a 25% lower risk of postoperative pain (risk ratio, 0.75; 95% confidence interval, 0.60-0.94) than the standard protocol.

CONCLUSIONS

Patients infrequently use opiates after ambulatory urogynecologic surgery. The use of a multimodal pain protocol was associated with lower pain scores, and patients in a multimodal pain protocol were more likely to report no pain.

摘要

目的

本研究旨在确定多模式方案对日间妇科泌尿手术患者术后阿片类药物使用和术后疼痛的影响。

方法

这是一项回顾性队列研究,比较了在标准围手术期疼痛方案下治疗的日间妇科泌尿手术患者与在多模式围手术期疼痛方案下治疗的患者。多模式方案包括术前加巴喷丁和对乙酰氨基酚,以及术后计划给予对乙酰氨基酚和非甾体抗炎药。疼痛评分根据医院方案从护理记录中获得,并采用数字评分量表(Numeric Rating Scale)11 进行评估。所有阿片类药物剂量均通过标准化换算表转换为吗啡毫克当量。

结果

我们在标准方案下治疗了 109 例患者,在多模式方案下治疗了 112 例患者。患者具有相似的基线特征。总体而言,少数患者(39%)使用了术后阿片类药物;两组间无差异(P=0.45)。两组术后吗啡毫克当量总量也相似(P=0.35)。在术后,接受标准方案治疗的患者疼痛评分较高(2.2 对 1.4,P=0.002)。与接受多模式方案治疗的患者相比(69%对 52%;P=0.01),接受标准方案治疗的患者更有可能报告术后疼痛,而多模式方案与术后疼痛风险降低 25%相关(风险比,0.75;95%置信区间,0.60-0.94)。

结论

患者在日间妇科泌尿手术后很少使用阿片类药物。多模式疼痛方案的使用与较低的疼痛评分相关,且在多模式疼痛方案下的患者更有可能报告无疼痛。

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Optimizing Perioperative Pain Control After Ambulatory Urogynecologic Surgery.优化门诊妇科泌尿手术围手术期疼痛控制。
Female Pelvic Med Reconstr Surg. 2020 Aug;26(8):483-487. doi: 10.1097/SPV.0000000000000775.

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