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在认知行为治疗的基础上添加应急管理对抑郁症吸烟者的增效作用:6 个月的戒烟和抑郁结果。

Additive effectiveness of contingency management on cognitive behavioural treatment for smokers with depression: Six-month abstinence and depression outcomes.

机构信息

Department of Psychology. University of Oviedo, Plaza Feijoo, s/n, 33003 Oviedo, Spain.

Department of Psychology. University of Oviedo, Plaza Feijoo, s/n, 33003 Oviedo, Spain.

出版信息

Drug Alcohol Depend. 2019 Nov 1;204:107495. doi: 10.1016/j.drugalcdep.2019.06.003. Epub 2019 Aug 24.

DOI:10.1016/j.drugalcdep.2019.06.003
PMID:31491583
Abstract

BACKGROUND

Depression and smoking co-occur at high rates and there is a lack of evidence on the efficacy of treatments specifically tailored to this population. This randomized controlled trial sought to compare the effectiveness of cognitive behavioural treatment (CBT) combined with behavioural activation (BA) and the same treatment protocol plus contingency management (CM).

METHODS

A sample of 120 adult smokers (70.8%: females) with severe depressive symptoms were randomly allocated to: CBT + BA (n = 60) or CBT + BA + CM (n = 60). Smoking and depression outcomes were reported at end of treatment, 1-, 2-, 3-, and 6-month follow-ups. Self-reported smoking status was biochemically verified, and depression was assessed using the Beck Depression Inventory-II.

RESULTS

At end of treatment, the overall quit rate was 69.2% (83/120). CM showed an additive effect on CBT + BA in enhancing abstinence rates. The significant effect of group [F(1,155) = 9.55, p =  .0024], time [F(4,96) = 7.93, p < .0001], and group by time interaction [F(4,96) = 6.12, p =  .0002], indicated that CM is more effective for generating longer durations of abstinence beyond those of CBT+BA. All treatment conditions equally promoted sustained reductions in depression across time [F(1,111) = 0.53, p =  .4665]. A greater number of days of continuous abstinence and lower depressive symptoms mutually influenced each other.

CONCLUSIONS

Depressed smokers achieve high cessation rates without suffering negative mood changes. Quitting smoking is not detrimental and adding CM to CBT + BA enhances long-lasting abstinence rates while promoting large depression improvements.

摘要

背景

抑郁和吸烟的发生率都很高,而且缺乏针对这一人群的治疗效果的证据。本随机对照试验旨在比较认知行为治疗(CBT)联合行为激活(BA)和相同治疗方案加条件管理(CM)的效果。

方法

将 120 名有严重抑郁症状的成年吸烟者(70.8%:女性)随机分配到 CBT+BA(n=60)或 CBT+BA+CM(n=60)组。在治疗结束时、1、2、3 和 6 个月的随访中报告吸烟和抑郁结果。使用贝克抑郁量表 II 评估自我报告的吸烟状况和抑郁状况。

结果

在治疗结束时,总的戒烟率为 69.2%(83/120)。CM 在提高 CBT+BA 的戒烟率方面显示出附加效应。组间[F(1,155)=9.55,p=.0024]、时间[F(4,96)=7.93,p<.0001]和组间时间交互作用[F(4,96)=6.12,p=.0002]的显著效应表明,CM 对产生更长时间的戒烟效果比 CBT+BA 更有效。所有治疗条件在时间上都能同等促进抑郁的持续降低[F(1,111)=0.53,p=.4665]。更多的连续戒烟天数和更低的抑郁症状相互影响。

结论

抑郁的吸烟者在不改变负面情绪的情况下可以达到较高的戒烟率。戒烟不会对情绪产生负面影响,而将 CM 加入 CBT+BA 中可以提高长期戒烟率,同时促进抑郁的大幅改善。

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