Grech Victor
Academic Department of Paediatrics, Medical School, Mater Dei Hospital, Malta.
Early Hum Dev. 2020 Jan;140:104856. doi: 10.1016/j.earlhumdev.2019.104856. Epub 2019 Sep 4.
This and the next series of Best Practise Guidelines will revisit the main theories that attempt to explain the influences on the sex ratio at birth (M/F), which was similarly reviewed in this journal in 2015. The papers include a historical review of the classical theories and initial work pertaining to the study of M/F, an analysis of 88,875,750 live births in an attempt to quantify M/F, the effect of earthquakes and climate change and an attempt to approximate the primary sex ratio (at conception). Another theoretical paper provides several potential explanations for autism spectrum disorder that may be correlated with M/F. Yet paper tests the hypothesis that RhD positive heterozygous mothers have a male-skewed sex ratio. A final paper provides a systematic review of the factors that influences M/F. It is hoped that this set of papers will continue to provide stimulation and food for thought on this intriguing topic.
本系列及下一系列最佳实践指南将重新审视一些主要理论，这些理论试图解释对出生性别比（男/女）的影响，本刊曾在2015年对其进行过类似回顾。这些论文包括对经典理论的历史回顾以及与出生性别比研究相关的初步工作、对88875750例活产进行分析以试图量化出生性别比、地震和气候变化的影响以及试图估算初级性别比（受孕时）。另一篇理论论文为自闭症谱系障碍提供了几种可能与出生性别比相关的潜在解释。还有一篇论文检验了RhD阳性杂合子母亲出生性别比偏向男性的假设。最后一篇论文对影响出生性别比的因素进行了系统综述。希望这组论文能继续激发人们对这个有趣话题的思考并提供思考素材。
