Division of Infectious Diseases and Health Policy Research Institute, University of California Irvine School of Medicine, Irvine, California, USA.
J Hosp Infect. 2019 Nov;103(3):235-243. doi: 10.1016/j.jhin.2019.08.025. Epub 2019 Sep 5.
Body surface decolonization with chlorhexidine bathing and nasal mupirocin has become a simple solution for prevention of healthcare-associated infections. The clinical trial evidence for this practice will be reviewed to understand who benefits from this practice, for what reasons, and at what times. The method of bathing and nasal decolonization will also be discussed as proper application is needed for maximal effectiveness. Finally, the conflict between current effectiveness and future potential for fueling resistance is considered.
用洗必泰沐浴和莫匹罗星鼻腔涂抹进行体表去定植已经成为预防医源性感染的简单方法。将对这种做法的临床试验证据进行审查，以了解谁从这种做法中受益，为什么受益，以及在什么情况下受益。还将讨论沐浴和鼻腔去定植的方法，因为需要正确应用才能发挥最大效果。最后，还考虑了当前有效性与未来可能助长耐药性之间的冲突。
