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抑郁与疾病特异性治疗的关联。

Association between depression and disease-specific treatment.

机构信息

Department of Public Health, Yonsei University Graduate School, Seoul, Republic of Korea.

Department of Preventive Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea; Cardiovascular and Metabolic Diseases Etiology Research Center, Yonsei University College of Medicine, Seoul, Republic of Korea.

出版信息

J Affect Disord. 2020 Jan 1;260:124-130. doi: 10.1016/j.jad.2019.08.073. Epub 2019 Aug 23.

Abstract

BACKGROUND

Depression is a known risk factor for noncompliance to medical treatment. However, it remains unclear whether comorbidities alter the relationship between depression and treatment compliance. We explored whether depression is associated with disease-specific treatment service utilization.

METHODS

This cross-sectional study utilized data from 499,492 individuals who had at least one comorbidity in the Korean Community Health Survey, 2009-2013. Self-reported lifetime depression diagnosis by a physician, current depressive symptoms, and utilization of medical services were queried. The association between depression status and the use of overall treatment services was investigated using multiple logistic regression models and further stratified by use of specific medical treatment under conditions predefined with the Charlson Comorbidity Index (CCI).

RESULTS

Compared with non-depressed people, individuals with a "lifetime history of depression with current depressive symptom" showed higher odds of using overall medical treatment services in both men (OR=1.21, 95%CI: 1.00-1.47) and women (OR=1.13, 95% CI: 1.02-1.25). However, depressed individuals with CCI comorbidities (e.g., diabetes mellitus or angina) exhibited less utilization of treatment services than non-depressed individuals.

LIMITATIONS

The nature of the cross-sectional study limits the ability to infer a temporal causal relationship.

CONCLUSION

Overall, depressed individuals with a lifetime history of depression used treatment services more frequently than non-depressed individuals; however, depressed individuals with major illnesses tended to seek treatment for their medical conditions less. The mental health of patients who seek for medical services should be carefully considered in primary care for the proper health service utilization.

摘要

背景

抑郁是不遵守医疗治疗的已知危险因素。然而,尚不清楚合并症是否改变了抑郁与治疗依从性之间的关系。我们探讨了抑郁是否与特定疾病的治疗服务利用有关。

方法

本横断面研究使用了 2009-2013 年韩国社区健康调查中至少有 1 种合并症的 499492 个人的数据。通过医生询问了终生抑郁诊断、当前抑郁症状和医疗服务的使用情况。使用多因素逻辑回归模型调查了抑郁状态与整体治疗服务使用之间的关系,并根据 Charlson 合并症指数 (CCI) 预先确定的条件进一步分层分析了特定医疗治疗的使用情况。

结果

与非抑郁者相比,患有“有当前抑郁症状的终生抑郁史”的个体在男性(OR=1.21,95%CI:1.00-1.47)和女性(OR=1.13,95%CI:1.02-1.25)中使用整体医疗服务的可能性更高。然而,患有 CCI 合并症(如糖尿病或心绞痛)的抑郁者比非抑郁者接受治疗的可能性更小。

局限性

横断面研究的性质限制了推断时间因果关系的能力。

结论

总体而言,有终生抑郁史的抑郁个体比非抑郁个体更频繁地使用治疗服务;然而,患有主要疾病的抑郁个体往往较少寻求治疗他们的疾病。在初级保健中,应仔细考虑寻求医疗服务的患者的心理健康,以实现适当的医疗服务利用。

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