第十一届 ENBDC 研讨会：技术进步有助于揭示乳腺发育和癌变的机制。
The Eleventh ENBDC Workshop: Advances in Technology Help to Unveil Mechanisms of Mammary Gland Development and Cancerogenesis.
机构信息
Department of Biomedicine, University of Basel, Basel, Switzerland.
Turku Bioscience Centre, University of Turku and Åbo Akademi University, Turku, Finland.
出版信息
J Mammary Gland Biol Neoplasia. 2019 Sep;24(3):201-206. doi: 10.1007/s10911-019-09436-0. Epub 2019 Sep 7.
The eleventh annual workshop of the European Network for Breast Development and Cancer, Methods in mammary gland biology and breast cancer, took place on the 16th to 18th of May 2019 in Weggis, Switzerland. The main topics of the meeting were high resolution genomics and proteomics for the study of mammary gland development and cancer, breast cancer signaling, tumor microenvironment, preclinical models of breast cancer, and tissue morphogenesis. Exciting novel findings in, or highly relevant to, mammary gland biology and breast cancer field were presented, with insights into the methods used to obtain them. Among others, the discussed methods included single-cell RNA sequencing, genetic barcoding, lineage tracing, spatial transcriptomics, optogenetics, genetic mouse models and organoids.
欧洲乳腺发育与癌症网络第十一届年会，乳腺生物学与乳腺癌方法，于 2019 年 5 月 16 日至 18 日在瑞士韦吉斯举行。会议的主要议题是乳腺发育和癌症的高分辨率基因组学和蛋白质组学、乳腺癌信号转导、肿瘤微环境、乳腺癌的临床前模型和组织形态发生。会议展示了乳腺生物学和乳腺癌领域的令人兴奋的新发现，或与之密切相关的发现，并深入了解了获得这些发现的方法。其中讨论的方法包括单细胞 RNA 测序、遗传条形码、谱系追踪、空间转录组学、光遗传学、遗传小鼠模型和类器官。
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