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尼日利亚儿童炎症性肠病:病例系列和管理挑战。

Inflammatory bowel disease in Nigerian children: case series and management challenges.

机构信息

Department of Paediatrics and Child Health, Lagos State University College of Medicine , Ikeja, Lagos, Nigeria.

Department of Paediatrics and Child Health, Lagos State University Teaching Hospital , Ikeja, Lagos State, Nigeria.

出版信息

Paediatr Int Child Health. 2020 Aug;40(3):143-147. doi: 10.1080/20469047.2019.1662658. Epub 2019 Sep 9.

DOI:10.1080/20469047.2019.1662658
PMID:31495301
Abstract

Inflammatory bowel disease (IBD) is rare in sub-Saharan Africa. Five cases in Nigerian children are presented to highlight the occurrence, pattern of clinical presentation and management challenges. The patients were identified following a retrospective review of all diagnosed cases of IBD between 1 January 2011 and 31 December 2018 seen at the Paediatric Gastroenterology, Hepatology and Nutrition Unit of Lagos State University Teaching Hospital. The median age (range) was 9 (7-13) years. Three cases were diagnosed because bloody diarrhoea persisted despite treatment at various health facilities for its common causes in the tropics and sub-tropics. The other two cases were confirmed after surgical intervention undertaken for symptoms of acute abdomen owing to appendicitis and intestinal obstruction. IBD should be considered in the differential diagnosis of children with chronic symptoms of bloody diarrhoea, weight loss, abdominal pain or abdominal masses.

摘要

炎症性肠病(IBD)在撒哈拉以南非洲很少见。本文介绍了 5 例尼日利亚儿童病例,以强调其发病情况、临床表现模式和管理挑战。这些患者是通过对 2011 年 1 月 1 日至 2018 年 12 月 31 日期间在拉各斯州立大学教学医院儿科胃肠病学、肝脏病学和营养学系诊断的所有 IBD 病例进行回顾性分析后确定的。中位年龄(范围)为 9(7-13)岁。3 例患者因在热带和亚热带常见病因的各种医疗机构接受治疗后仍持续出现血性腹泻而被诊断为 IBD。另外 2 例患者因急性阑尾炎和肠梗阻的症状而接受手术干预后被确诊为 IBD。对于有慢性血性腹泻、体重减轻、腹痛或腹部包块症状的儿童,应考虑 IBD 作为鉴别诊断。

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引用本文的文献

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Nutritional deficiencies and associated pathologies present unique challenges of diagnosing paediatric inflammatory bowel disease in sub-Saharan Africa.营养缺乏及相关病症给撒哈拉以南非洲地区小儿炎症性肠病的诊断带来了独特挑战。
BMJ Nutr Prev Health. 2024 Nov 14;7(2):e001098. doi: 10.1136/bmjnph-2024-001098. eCollection 2024.
2
Inflammatory Bowel Disease On-Line Web-Based Guide to Health Professionals and Patients in Developing and African Nations.炎症性肠病在线网络指南:面向发展中国家和非洲国家的医疗专业人员及患者
Jpn J Gastroenterol Hepatol. 2020;3(2). Epub 2020 Mar 11.
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Inflammatory Bowel Disease in Children: Experience and Constraints in a Resource-limited Setting.
儿童炎症性肠病:资源有限环境下的经验与限制
Cureus. 2020 Apr 27;12(4):e7848. doi: 10.7759/cureus.7848.