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全肩关节置换术后住院患者阿片类药物消耗的变化研究:患者和外科医生相关因素的影响。

Study of variations in inpatient opioid consumption after total shoulder arthroplasty: influence of patient- and surgeon-related factors.

机构信息

Shoulder and Elbow Division, Department of Orthopaedic Surgery, NYU Langone Orthopedic Hospital, New York, NY, USA.

Shoulder and Elbow Division, Department of Orthopaedic Surgery, NYU Langone Orthopedic Hospital, New York, NY, USA.

出版信息

J Shoulder Elbow Surg. 2020 Mar;29(3):508-515. doi: 10.1016/j.jse.2019.06.021. Epub 2019 Sep 5.

Abstract

BACKGROUND

The aims of this study were to examine variances in inpatient opioid consumption after total shoulder arthroplasty (TSA) and to determine factors influencing inpatient opioid utilization.

METHODS

The sample included patients undergoing elective TSA at a tertiary-level institution between January 2016 and April 2018. Opioid consumption during the inpatient stay was converted into morphine milligram equivalents (MMEs), accounting for dosage and route of administration. The MMEs were calculated per patient encounter and used to calculate mean opioid consumption. Bivariate linear regression analysis was performed to assess the impact of patient-related factors and surgery-related factors on inpatient opioid consumption.

RESULTS

Altogether 20 surgeons performed 622 TSAs. The average opioid dose per encounter was 47.4 ± 65.7 MME/d. MMEs prescribed varied significantly among surgeon providers (P < .01). Pre-existing psychiatric disorders (P = .00012), preoperative opioid use (P = .0013), highest quartile of median household income (P = .048), current-smoker status (P < .001), age < 60 years (P < .01), and general anesthesia (vs. regional anesthesia, P = .005) were associated with significant inpatient opioid consumption after TSA. Sex, race, American Society of Anesthesiologists status, replacement type (anatomic TSA vs. reverse TSA), and prior shoulder surgery did not show any significant differences.

CONCLUSION

There is considerable variation in inpatient opioid consumption after TSA at the same institution. Knowledge of modifiable and nonmodifiable risk factors that increase inpatient opioid consumption will help to optimize multimodal analgesia protocols for TSA.

摘要

背景

本研究旨在考察全肩关节置换术后(TSA)住院患者阿片类药物消耗的差异,并确定影响住院阿片类药物使用的因素。

方法

本研究纳入了 2016 年 1 月至 2018 年 4 月在一家三级医疗机构接受择期 TSA 的患者。住院期间的阿片类药物消耗换算成吗啡毫克当量(MME),考虑剂量和给药途径。根据每位患者的就诊情况计算 MME,用于计算平均阿片类药物消耗。采用双变量线性回归分析评估患者相关因素和手术相关因素对住院阿片类药物消耗的影响。

结果

共有 20 名外科医生完成了 622 例 TSA。每次就诊的平均阿片类药物剂量为 47.4 ± 65.7 MME/d。外科医生开具的 MME 处方存在显著差异(P <.01)。术前存在精神疾病(P =.00012)、术前使用阿片类药物(P =.0013)、家庭收入中位数最高四分位数(P =.048)、当前吸烟者状态(P <.001)、年龄<60 岁(P <.01)和全身麻醉(与区域麻醉相比,P =.005)与 TSA 后住院阿片类药物消耗显著相关。性别、种族、美国麻醉医师协会状态、置换类型(解剖型 TSA 与反式 TSA)和既往肩部手术无显著差异。

结论

同一机构 TSA 后住院阿片类药物消耗存在较大差异。了解增加住院阿片类药物消耗的可改变和不可改变的危险因素将有助于优化 TSA 的多模式镇痛方案。

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