Iizuka Yusuke, Iizuka-Ohashi Mahiro, Kawasaki Sumi, Nakai Ichiro, Mizowaki Takashi
Department of Radiation Oncology and Image-applied Therapy, Kyoto University Graduate School of Medicine.
Department of Breast Surgery, Kyoto Yamashiro General Medical Center.
Kaku Igaku. 2019;56(1):117-120. doi: 10.18893/kakuigaku.cr.1901.
The patient was a 47-year-old female with stage IV breast cancer and multiple bone metastases. She received various systemic therapies (hormone therapy and chemotherapy) and underwent mastectomy between 2013 and 2018; in the beginning of 2018, she started experiencing bone metastatic pain in the right hip joint and neural pain on the dorsal side of the left thigh. These symptoms worsened gradually, and nonsteroidal anti-inflammatory analgesics or narcotic analgesics were not effective for treating this pain. Strontium-89 (Sr) treatment was administered in April 2018. The pain was relieved immediately after Sr treatment. The patient's quality of life improved markedly. She spent her remaining life without using analgesic drugs, until she died in October 2018 due to exacerbation of the original disease. Although radiotherapy is believed to be less effective for neuropathic pain than for bone metastatic pain, it should be considered as a treatment option in patients with neuropathic pain.
该患者为一名47岁女性,患有IV期乳腺癌并伴有多处骨转移。她在2013年至2018年间接受了多种全身治疗(激素治疗和化疗)并接受了乳房切除术;2018年初,她开始出现右髋关节骨转移性疼痛和左大腿背侧神经痛。这些症状逐渐加重,非甾体类抗炎镇痛药或麻醉性镇痛药对治疗这种疼痛均无效。2018年4月给予了锶-89(Sr)治疗。Sr治疗后疼痛立即缓解。患者的生活质量明显改善。她在余生中未使用镇痛药,直至2018年10月因原发病加重而死亡。尽管放疗被认为对神经性疼痛的疗效不如对骨转移性疼痛,但对于神经性疼痛患者仍应将其视为一种治疗选择。