皮质类固醇节省维持免疫抑制/辅助治疗药物的药理学与治疗学

Pharmacology and Therapeutics of Corticosteroids Sparing Maintenance Immunosuppressive/Adjunct Therapy Drugs.

作者信息

Sehgal Virendra N, Malhotra Rajesh

机构信息

Dermato-Venereology (Skin/VD) Centre, Sehgal Nursing Home, New Delhi, India;

Department of Orthopaedics, All India Institute of Medical Sciences, New Delhi, India.

出版信息

Skinmed. 2019 Sep 9;17(3):172-179. eCollection 2019.

PMID:31496471

Abstract

Glucocorticoids, corticosteroids/steroids sparing (replacement) maintenance immunosuppressive/adjunct drugs delivery has always been a challenging overture. Azathioprine, cyclophosphamide, dapsone, immunoglobulin, and interferon are agents in this category. The pharmacology and pharmacokinetics of the preceding drugs include specific recommendations, generic names, availability, mode of administration, dosage schedule, and the essentials of drug management.

摘要

糖皮质激素、皮质类固醇/甾体类药物节省（替代）维持免疫抑制/辅助药物的给药一直是一项具有挑战性的开端。硫唑嘌呤、环磷酰胺、氨苯砜、免疫球蛋白和干扰素都属于这一类药物。上述药物的药理学和药代动力学包括具体建议、通用名称、可获得性、给药方式、剂量方案以及药物管理要点。