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高强度聚焦超声与等离子射频消融治疗复发性变应性鼻炎的效果比较。

Effect of High-Intensity Focused Ultrasound Versus Plasma Radiofrequency Ablation on Recurrent Allergic Rhinitis.

机构信息

Department of Otolaryngology - Head and Neck Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, China (mainland).

出版信息

Med Sci Monit. 2019 Sep 9;25:6775-6781. doi: 10.12659/MSM.916228.

Abstract

BACKGROUND High-intensity focused ultrasound (HIFU) and plasma radiofrequency ablation (PRA) have been used to treat recurrent allergic rhinitis (AR); however, there is a lack of literature comparing the efficacy of these 2 methods. We assessed and compared the therapeutic effects of HIFU and PRA on recurrent AR. MATERIAL AND METHODS We enrolled 66 patients with recurrent AR at West China Hospital of Sichuan University. Visual analogue score (VAS), pain score, rhinoconjunctivitis quality of life questionnaire (RQLQ), and nasal endoscopy were performed to evaluate the therapeutic effect. RESULTS Nasal endoscopy showed that HIFU and PAR reduced the volume of the inferior turbinate, whereas HIFU reduced the amount of nasal secretions in patients. VAS scores showed that HIFU and PRA nasal congestion symptoms were significantly reduced (P<0.05). The preoperative VAS scores for nasal fluid and sneezing were significantly lower in patients receiving HIFU (P<0.05) than in those receiving PRA (P>0.05). HIFU-treated patients had significantly lower postoperative pain scores than those in the PRA group (P<0.05). RQLQ showed activity, sleep, and non-nasal or ocular symptoms, and both HIFU and PRA patients had significantly lower scores (P<0.05). Nasal symptom scores, actual problems, and mood in the HIFU group were significantly worse than those in the PRA group (P<0.05). However, neither treatment had a significant effect on ocular symptoms (P>0.05). CONCLUSIONS Compared with PRA, HIFU can significantly reduce the nasal symptoms of AR patients, improve the quality of life, and can be used as an adjuvant therapy with better therapeutic effect.

摘要

背景

高强度聚焦超声(HIFU)和等离子射频消融(PRA)已用于治疗复发性过敏性鼻炎(AR);然而,缺乏比较这 2 种方法疗效的文献。我们评估和比较了 HIFU 和 PRA 治疗复发性 AR 的疗效。

材料和方法

我们纳入了四川大学华西医院的 66 例复发性 AR 患者。采用视觉模拟评分(VAS)、疼痛评分、鼻结膜炎生活质量问卷(RQLQ)和鼻内镜检查评估治疗效果。

结果

鼻内镜检查显示 HIFU 和 PRA 均减小了下鼻甲的体积,而 HIFU 减少了患者的鼻腔分泌物量。VAS 评分显示 HIFU 和 PRA 均明显减轻了鼻塞症状(P<0.05)。接受 HIFU 治疗的患者的术前 VAS 评分在鼻腔分泌物和打喷嚏方面明显低于接受 PRA 治疗的患者(P<0.05)。接受 HIFU 治疗的患者术后疼痛评分明显低于 PRA 组(P<0.05)。RQLQ 显示活动、睡眠、非鼻部或眼部症状,HIFU 和 PRA 患者的评分均明显降低(P<0.05)。HIFU 组的鼻部症状评分、实际问题和情绪明显差于 PRA 组(P<0.05)。然而,两种治疗方法对眼部症状均无明显影响(P>0.05)。

结论

与 PRA 相比,HIFU 可显著减轻 AR 患者的鼻部症状,提高生活质量,可作为一种辅助治疗方法,疗效更好。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3012/6752098/6808e9996130/medscimonit-25-6775-g001.jpg

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