Foumani Ali Alavi, Neyaragh Mohammad Masoud, Ranjbar Zahra Abbasi, Leyli Ehsan Kazemnezhad, Ildari Shima, Jafari Alireza
Inflammatory Lung Disease Research Center, Department of Internal Medicine, Razi Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran.
Department of Internal Medicine, Student Research Committee, Faculty of Medicine, Guilan University of Medical Sciences, Rasht, Iran.
Osong Public Health Res Perspect. 2019 Aug;10(4):240-245. doi: 10.24171/j.phrp.2019.10.4.07.
The aim of this study was to evaluate whether the waist circumference of patients with chronic obstructive pulmonary disease (COPD), had an impact on lung function.
There were 180 patients with COPD recruited into this prospective cross-sectional study. The age, weight, body mass index and waist circumference (WC) were measured. Spirometry parameters including forced vital capacity (FVC), and forced expiratory volume in the first second (FEV1), were measured and FEV1/FVC calculated.
The mean FEV1/FVC in both normal weight and overweight patients, did not statistically significantly correlate with WC. The COPD assessment test, positively correlated with WC ( = 0.031). A positive correlation with body mass index ( < 0.001), smoking ( = 0.027), and global initiative for chronic obstructive lung disease score ( = 0.009), were observed to positively associate with WC. WC, age, C-reactive protein, duration of disease, and gender (male), were observed to be statistically significant risk factors for the severity of COPD.
WC was not observed to impact upon lung function in this study but it was a predictive factor for COPD severity in patients.
本研究旨在评估慢性阻塞性肺疾病（COPD）患者的腰围是否对肺功能有影响。
180例COPD患者被纳入这项前瞻性横断面研究。测量了年龄、体重、体重指数和腰围（WC）。测量了肺量计参数，包括用力肺活量（FVC）和第1秒用力呼气量（FEV1），并计算了FEV1/FVC。
正常体重和超重患者的平均FEV1/FVC与WC无统计学显著相关性。COPD评估测试与WC呈正相关（=0.031）。观察到与体重指数（<0.001）、吸烟（=0.027）和慢性阻塞性肺疾病全球倡议评分（=0.009）呈正相关，且与WC呈正相关。观察到WC、年龄、C反应蛋白、疾病持续时间和性别（男性）是COPD严重程度的统计学显著危险因素。
在本研究中未观察到WC对肺功能有影响，但它是患者COPD严重程度的一个预测因素。
