Masuda T, Satodate R, Suzuki K, Sato S
Department of Pathology, School of Medicine, Iwate Medical University, Morioka.
Tohoku J Exp Med. 1988 Dec;156(4):375-9. doi: 10.1620/tjem.156.375.
Nuclear deformity of hepatocytes was measured using two parameters, the form factor and the axial ratio, in liver biopsy specimens from 29 patients with acute viral hepatitis (AVH). Another 13 patients with chronic persistent hepatitis (CPH) were added as control. Nuclear deformity of hepatocytes was morphometrically confirmed to increase in AVH compared to that in CPH. This was related to the regeneration of hepatocytes.