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经皮迷走神经刺激治疗延髓外侧梗死后吞咽困难 1 例报告

Effect of Transcutaneous Vagus Nerve Stimulation in Dysphagia After Lateral Medullary Infarction: A Case Report.

机构信息

Department of Rehabilitation, Xuanwu Hospital Capital Medical University, Beijing, China.

Department of Rehabilitation, Wangjing Hospital of China Academy of Chinese Medical Science, Beijing.

出版信息

Am J Speech Lang Pathol. 2019 Nov 19;28(4):1381-1387. doi: 10.1044/2019_AJSLP-18-0262. Epub 2019 Sep 6.

DOI:10.1044/2019_AJSLP-18-0262
PMID:31498703
Abstract

Purpose Severe dysphagia with weak pharyngeal peristalsis after dorsal lateral medullary infarction (LMI) requires long-term tube feeding. However, no study is currently available on therapeutic effectiveness in severe dysphagia caused by nuclear damage of vagus nerve after dorsal LMI. The purpose of the present investigation was to explore the potential of transcutaneous vagus nerve stimulation (tVNS) to improve severe dysphagia with weak pharyngeal peristalsis after dorsal LMI. Method We assessed the efficacy of 6-week tVNS in a 28-year-old woman presented with persisting severe dysphagia after dorsal LMI who had been on nasogastric feeding for 6 months. tVNS was applied for 20 min twice a day, 5 days a week, for 6 weeks. The outcome measures included saliva spitted, Swallow Function Scoring System, Functional Oral Intake Scale, Clinical Assessment of Dysphagia With Wallenberg Syndrome, Yale Pharyngeal Residue Severity Rating Scale, and upper esophagus X-ray examination. Results After tVNS, the patient was advanced to a full oral diet without head rotation or spitting. No saliva residue was found in the valleculae and pyriform sinuses. Contrast medium freely passed through the upper esophageal sphincter. Conclusion Our findings suggest that tVNS might provide a useful means for recovery of severe dysphagia with weak pharyngeal peristalsis after dorsal LMI. Supplemental Material https://doi.org/10.23641/asha.9755438.

摘要

目的

延髓背外侧梗死(LMI)后出现严重吞咽困难伴咽缩肌无力者需要长期管饲。然而,目前尚无关于 LMI 后迷走神经核损伤所致严重吞咽困难的治疗效果的研究。本研究旨在探讨经皮迷走神经刺激(tVNS)治疗延髓背外侧梗死后严重吞咽困难伴咽缩肌无力的潜力。

方法

我们评估了 6 周 tVNS 对 1 例 28 岁女性的疗效,该女性在 LMI 后持续存在严重吞咽困难,已行鼻饲喂养 6 个月。tVNS 每天应用 2 次,每次 20 分钟,每周 5 天,共 6 周。评估结果包括唾液咳出、吞咽功能评分系统、功能性口腔摄入量表、延髓外侧综合征吞咽临床评估、耶鲁咽后残留严重程度评分量表和食管上 X 线检查。

结果

tVNS 后,患者可经口进食全量饮食,无需转头或咳痰。在会厌谷和梨状隐窝无唾液残留。造影剂可自由通过食管上括约肌。

结论

我们的研究结果表明,tVNS 可能为治疗 LMI 后严重吞咽困难伴咽缩肌无力提供一种有用的方法。

补充材料

https://doi.org/10.23641/asha.9755438.

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