Oishei Children's Hospital, Dept. of Anesthesiology Jacobs School of Medicine and Biomedical Sciences, Buffalo, New York, USA.
Curr Opin Anaesthesiol. 2019 Dec;32(6):708-713. doi: 10.1097/ACO.0000000000000787.
Ambulatory surgery is the standard for the majority of pediatric surgery in 2019 and adenotonsillectomy is the second most common ambulatory surgery in children so it is an apt paradigm. Preparing and managing these children as ambulatory patients requires a thorough understanding of the current literature.
The criteria for undertaking pediatric adenotonsillectomy on an ambulatory basis, fasting after clear fluids, postoperative nausea and vomiting (PONV), perioperative pain management and discharge criteria comprise the themes addressed in this review.
Three criteria determine suitability of adenotonsillectomy surgery on an ambulatory basis: the child's age, comorbidities and the severity of the obstructive sleep apnea syndrome (OSAS). Diagnosing OSAS in children has proven to be a challenge resulting in alternate, noninvasive techniques, which show promise. Abbreviating the 2 h clear fluid fasting guideline has garnered attention, although the primary issue is that parents do not follow the current clear fluid fasting regimen and until that is resolved, consistent fasting after clear fluids will remain elusive. PONV requires aggressive prophylactic measures that fail in too many children. The importance of unrecognized genetic polymorphisms in PONV despite prophylactic treatment is understated as are the future roles of palonosetron and Neurokinin-1 receptor antagonists that may completely eradicate PONV when combined with dexamethasone. Pain management requires test doses of opioids intraoperatively in children with OSAS and nocturnal desaturation to identify those with reduced opioid dosing thresholds, an uncommon practice as yet. Furthermore, postdischarge nonsteroidal anti-inflammatory agents as well as other pain management strategies should replace oral opioids to prevent respiratory arrests in those who are ultra-rapid CYP2D6 metabolizers. Finally, discharge criteria are evolving and physiological-based criteria should replace time-based, reducing the risk of readmission.
2019 年,大部分儿科手术都采用日间手术模式,而腺样体扁桃体切除术是儿童中第二常见的日间手术,因此它是一个合适的范例。为了将这些儿童作为日间手术患者进行准备和管理,需要对当前文献有透彻的了解。
开展儿童日间腺样体扁桃体切除术的标准、术后恶心呕吐(PONV)的禁食时间、围手术期疼痛管理和出院标准是本次综述的主题。
有三个标准决定了腺样体扁桃体切除术是否适合在日间进行:儿童的年龄、合并症和阻塞性睡眠呼吸暂停综合征(OSAS)的严重程度。在儿童中诊断 OSAS 已被证明是一个挑战,这导致了替代的、非侵入性的技术,这些技术显示出了希望。缩短 2 小时清液禁食指南引起了关注,尽管主要问题是父母不遵守当前的清液禁食方案,在这一问题得到解决之前,持续禁食清液仍难以实现。PONV 需要积极的预防措施,但在太多儿童中失败。尽管预防性治疗,但PONV 中未被识别的遗传多态性的重要性被低估了,而 palonosetron 和神经激肽-1 受体拮抗剂的未来作用也被低估了,当与地塞米松联合使用时,它们可能会完全消除 PONV。疼痛管理需要在有 OSAS 和夜间血氧饱和度降低的儿童中进行术中阿片类药物测试剂量,以确定那些阿片类药物剂量阈值降低的儿童,这是一种尚未普及的做法。此外,出院后使用非甾体抗炎药以及其他疼痛管理策略应该取代口服阿片类药物,以防止那些超快 CYP2D6 代谢者出现呼吸暂停。最后,出院标准正在发展,基于生理的标准应该取代基于时间的标准,从而降低再次入院的风险。