Lesbian, Gay, and Bisexual Adults have Higher Prevalence of Illicit Opioid Use than Heterosexual Adults: Evidence from the National Survey on Drug Use and Health, 2015-2017.

We estimated illicit opioid use prevalence among LGB and heterosexual adults. Cross-sectional National Survey on Drug Use and Health data (2015-2017) were used to estimate illicit opioid use prevalence by sexual identity, age, and gender. An estimated 1.1 million LGB adults used illicit opioids in the preceding 12 months (LGB adults: 9.8%; heterosexual adults: 4.24%). Prevalence of illicit opioid use was significantly higher among LGB women aged <50 and gay/bisexual men (18-25 and 50 +) compared with their heterosexual counterparts. Interventions targeting LGB illicit opioid use should account for possible differential minority stress associated with age and gender.