Shizukuda Y, Murakami H, Iwakura M, Hashimoto A, Tsuchihashi K, Yonekura S, Tanaka S, Shimamoto K, Sato M, Iimura O
Second Department of Internal Medicine, Sapporo Medical College.
J Cardiol. 1988 Sep;18(3):867-74.
This report describes very rare siblings who had a left ventricular muscular diverticulum and hypertrophic cardiomyopathy. The first case is a 16-year-old male. On two-dimensional echocardiography, a left ventricular muscular diverticulum in the posterior wall and mitral valve prolapse were detected. The former was verified by left ventriculography. Endomyocardial biopsy showed findings compatible with hypertrophic cardiomyopathy. The second case is a 13-year-old female. Two-dimensional echocardiography revealed a left ventricular muscular diverticulum in the same location as that of the first case, and mitral valve prolapse as well. The former was confirmed by left ventriculography. The endomyocardial biopsy findings were compatible with hypertrophic cardiomyopathy. The coronary angiograms were normal in both cases. To our knowledge, familial appearance of a left ventricular diverticulum has not yet been reported, and a left ventricular diverticulum at the posterior wall in cases with hypertrophic cardiomyopathy is very rare.
本报告描述了患有左心室肌性憩室和肥厚型心肌病的极为罕见的同胞兄妹。首例为一名16岁男性。二维超声心动图检查发现后壁存在左心室肌性憩室及二尖瓣脱垂。前者经左心室造影证实。心内膜活检结果符合肥厚型心肌病。第二例为一名13岁女性。二维超声心动图显示与首例相同位置存在左心室肌性憩室，同时也有二尖瓣脱垂。前者经左心室造影确认。心内膜活检结果符合肥厚型心肌病。两例患者的冠状动脉造影均正常。据我们所知，左心室憩室的家族性表现尚未见报道，肥厚型心肌病患者后壁出现左心室憩室非常罕见。
