Jin Xiao-Ling, Zhang Miao, Zhou Zhongyun, Yu Xiaoyu
Management School, Shanghai University, Shanghai, China.
Department of Management Science and Engineering, School of Economics and Management, Tongji University, Shanghai, China.
J Med Internet Res. 2019 Sep 10;21(9):e13587. doi: 10.2196/13587.
The rapid development of genetic and genomic technologies, such as next-generation sequencing and genome editing, has made disease treatment much more precise and effective. The technologies' value can only be realized by the aggregation and analysis of people's genomic and health data. However, the collection and sharing of genomic data has many obstacles, including low data quality, information islands, tampering distortions, missing records, leaking of private data, and gray data transactions.
This study aimed to prove that emerging blockchain technology provides a solution for the protection and management of sensitive personal genomic data because of its decentralization, traceability, encryption algorithms, and antitampering features.
This paper describes the case of a blockchain-based genomic big data platform, LifeCODE.ai, to illustrate the means by which blockchain enables the storage and management of genomic data from the perspectives of data ownership, data sharing, and data security.
Blockchain opens up new avenues for dealing with data ownership, data sharing, and data security issues in genomic big data platforms and realizes the psychological empowerment of individuals in the platform.
The blockchain platform provides new possibilities for the management and security of genetic data and can help realize the psychological empowerment of individuals in the process, and consequently, the effects of data self-governance, incentive-sharing, and security improvement can be achieved. However, there are still some problems in the blockchain that have not been solved, and which require continuous in-depth research and innovation in the future.
基因和基因组技术的快速发展，如下一代测序和基因组编辑，使疾病治疗更加精确和有效。这些技术的价值只有通过对人们的基因组和健康数据进行汇总和分析才能实现。然而，基因组数据的收集和共享存在诸多障碍，包括数据质量低、信息孤岛、篡改失真、记录缺失、私人数据泄露以及灰色数据交易等。
本研究旨在证明新兴的区块链技术因其去中心化、可追溯性、加密算法和防篡改特性，为敏感个人基因组数据的保护和管理提供了一种解决方案。
本文描述了一个基于区块链的基因组大数据平台LifeCODE.ai的案例，从数据所有权、数据共享和数据安全的角度说明区块链实现基因组数据存储和管理的方式。
区块链为处理基因组大数据平台中的数据所有权、数据共享和数据安全问题开辟了新途径，并实现了平台中个人的心理赋权。
区块链平台为基因数据的管理和安全提供了新的可能性，并有助于在这一过程中实现个人的心理赋权，从而实现数据自我治理、激励共享和安全提升的效果。然而，区块链仍存在一些尚未解决的问题，未来需要持续深入研究和创新。
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