Leal Marcelle Lemos, Maciel Ethel Leonor Nóia, Cade Nágela Valadão
Programa de Pós-Graduação em Saúde Coletiva, Centro de Ciências da Saúde, Universidade Federal do Espírito Santo. Av. Marechal Campos 1468, Maruípe. 29040-091 Vitória ES Brasil.
Cien Saude Colet. 2019 Sep 9;24(9):3247-3256. doi: 10.1590/1413-81232018249.30392017. Print 2018 Feb 11.
This study analyzed the factors associated with tuberculosis in diabetics seen at health units of Vitória, ES, Brazil. This is a case-control study of 45 cases of diabetics seen in the 30 units of the municipality and reported in the SINAN with a diagnosis of tuberculosis in the 2007-2013 period and 90 cases of diabetic controls. We used data from the SINAN, the Health Information System of Vitória, and the Central Municipal Laboratory, as well a structured interview. Bivariate and multivariate analyses were performed, using logistic regression with the significant variables (p < 0.05). The case group presented a higher frequency of health-damaging life habits as compared to the control group, such as compulsive drinking (p < 0.001) and tobacco smoking (p = 0.060), as well as worse biochemical parameters, such as fasting blood sugar (p < 0.001) and glycosylated hemoglobin (p = 0.034). Regular drinking (OR 6.612, CI 2,151-20.330), previous contact with people with tuberculosis (OR 4.418, CI 1.678-11.631), and fasting blood sugar (OR 1.017, CI 1.007-1.026) were associated with tuberculosis in diabetics. The study reveals that poorer lifestyle habits and glycemic control and previous contact with active tuberculosis increase the chance of diabetics developing tuberculosis.
本研究分析了巴西圣埃斯皮里图州维多利亚市卫生单位中糖尿病患者患结核病的相关因素。这是一项病例对照研究，研究对象为该市30个卫生单位中确诊的45例糖尿病患者，这些患者在2007 - 2013年期间被巴西全国疾病通报系统（SINAN）报告患有结核病，以及90例糖尿病对照患者。我们使用了来自SINAN、维多利亚市卫生信息系统和市中央实验室的数据，以及结构化访谈。进行了双变量和多变量分析，采用逻辑回归分析显著变量（p < 0.05）。与对照组相比，病例组出现有害健康生活习惯的频率更高，如强迫性饮酒（p < 0.001）和吸烟（p = 0.060），以及生化指标更差，如空腹血糖（p < 0.001）和糖化血红蛋白（p = 0.034）。经常饮酒（比值比6.612，置信区间2.151 - 20.330）、既往与结核病患者接触（比值比4.418，置信区间1.678 - 11.631）和空腹血糖（比值比1.017，置信区间1.007 - 1.026）与糖尿病患者患结核病有关。该研究表明，较差的生活方式习惯、血糖控制以及既往与活动性结核病患者接触会增加糖尿病患者患结核病的几率。
