Tsukamoto Shinji, Mavrogenis Andreas F, Tanzi Piergiuseppe, Leone Giulio, Akahane Manabu, Tanaka Yasuhito, Errani Costantino
Department of Orthopaedic Surgery, Nara Medical University, Nara, Japan.
First Department of Orthopaedics, School of Medicine, National and Kapodistrian University of Athens, 41 Ventouri Str., 15562, Athens, Greece.
Eur J Orthop Surg Traumatol. 2020 Jan;30(1):3-9. doi: 10.1007/s00590-019-02535-y. Epub 2019 Sep 13.
We reviewed the files of 203 patients with extremities GCTB treated with curettage as first surgery from 1990 to 2013. Median follow-up was 84.2 months. We evaluated whether the years of practice and training in orthopaedic oncology are associated with local recurrences, function and complications after curettage as first surgery for giant cell tumour of bone (GCTB). Local recurrences were not significantly different between orthopaedic oncology trained and non-trained orthopaedic surgeons and between orthopaedic surgeons with < 10 years and ≥ 10 years of practice. Function was not significantly different between orthopaedic oncology trained and non-trained surgeons and between orthopaedic surgeons with < 10 years and ≥ 10 years of practice. The only important univariate and multivariate predictor for local recurrence was PMMA adjuvant. Complications were not significantly different between orthopaedic oncology trained and non-trained orthopaedic surgeons and between orthopaedic surgeons with < 10 years and ≥ 10 years of practice. Curettage may be effectively performed as first surgery for GCTB by early-career (< 10 years of practice) non-trained orthopaedic oncology orthopaedic surgeons. PMMA adjuvant is recommended after appropriate curettage.
我们回顾了1990年至2013年间接受刮除术作为首次手术治疗的203例四肢骨巨细胞瘤(GCTB)患者的病历。中位随访时间为84.2个月。我们评估了骨科肿瘤学方面的实践年限和培训是否与骨巨细胞瘤(GCTB)首次手术刮除术后的局部复发、功能及并发症相关。接受过骨科肿瘤学培训和未接受过培训的骨科医生之间,以及执业年限<10年和≥10年的骨科医生之间,局部复发情况无显著差异。接受过骨科肿瘤学培训和未接受过培训的外科医生之间,以及执业年限<10年和≥10年的骨科医生之间,功能无显著差异。局部复发唯一重要的单变量和多变量预测因素是聚甲基丙烯酸甲酯(PMMA)辅助治疗。接受过骨科肿瘤学培训和未接受过培训的骨科医生之间,以及执业年限<10年和≥10年的骨科医生之间,并发症无显著差异。初出茅庐(执业年限<10年)且未接受过培训的骨科肿瘤学骨科医生可有效地将刮除术作为GCTB的首次手术。建议在适当刮除术后使用PMMA辅助治疗。