Guillemin C
Ann Genet. 1979 Jun;22(2):77-84.
In the newt Pleurodelles waltlii, males and females trisomic for chromosomes 8, 10 and 11 are fertile. Crosses between such trisomics and diploids were carried out. Progeny analysis showed that an extra chromosome is transmitted to half of the gametes of both males and females trisomics. The extra chromosome apparently causes interference in the regular mechanics of meiotic division, so that trisomics throw nonparental aneuploids and polyploids in their progenies. Moreover, some descendants develop chromosome anomalies during embryonic life ; thus, the progeny of trisomics include diploids, parentaltype trisomics, and embryos with new chromosome anomalies. Morphology and chromosome anomalies of the embryos are compared. A possible explanation for the secondarily acquired anomalies are discussed.
在美西螈（Pleurodelles waltlii）中，8号、10号和11号染色体三体的雄性和雌性是可育的。进行了此类三体与二倍体之间的杂交。子代分析表明，额外的一条染色体被传递给雄性和雌性三体的一半配子。这条额外的染色体显然会干扰减数分裂的正常机制，因此三体会在其后代中产生非亲本非整倍体和多倍体。此外，一些后代在胚胎期会出现染色体异常；因此，三体的后代包括二倍体、亲本型三体以及具有新染色体异常的胚胎。对胚胎的形态和染色体异常进行了比较。讨论了二次获得性异常的一种可能解释。
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