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正常生育男性与不育男性精浆中的缓激肽酶和蛋白酶抑制剂

Bradykininase and protease inhibitors in seminal plasma of fertile and infertile men.

作者信息

Gecse A, Ottlecz A, Török L, Telegdy G, Morvay J, Sas M

出版信息

Arch Androl. 1979 Jun;2(4):311-6. doi: 10.3109/01485017908987331.

Abstract

The level of protease acrosin in the seminal plasma of oligozoospermic men was significantly higher than that of normozoospermic men. The amount of bradykininase in the seminal plasma was very high in both normozoospermic and oligozoospermic patients. When the acrosin and kininase content was referred to one million spermatozoa, seminal plasma kininase was significantly enhanced in oligozoospermic men, while the acrosin activity was similar in normozoospermic fertile men and infertile men. Human seminal plasma inhibitor I (HUSI I) increased along with sperm count. Human seminal plasma inhibitor II (HUSI II) showed no change. The motility of spermatozoa was depressed in oligozoospermic patients.

摘要

少精子症男性精浆中顶体蛋白酶水平显著高于正常精子症男性。正常精子症和少精子症患者的精浆中缓激肽酶含量都非常高。当以100万个精子计算顶体蛋白酶和激肽酶含量时,少精子症男性精浆中的激肽酶显著增加,而正常精子症可育男性和不育男性的顶体蛋白酶活性相似。人精浆抑制剂I(HUSI I)随精子计数增加而升高。人精浆抑制剂II(HUSI II)无变化。少精子症患者的精子活力降低。

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