Westergaard Maria Lurenda, Lau Cathrine Juel, Allesøe Karen, Gjendal Signe Thorup, Jensen Rigmor Højland
Danish Headache Center, Rigshospitalet Glostrup, Glostrup, Denmark.
Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, Frederiksberg, Denmark.
Cephalalgia. 2020 Jan;40(1):6-18. doi: 10.1177/0333102419876909. Epub 2019 Sep 15.
To study chronic headache and medication-overuse headache (MOH) prevalence; to identify groups with high prevalence of these conditions; and to identify the most frequently used pain medications among respondents with chronic headache.
Chronic headache and MOH prevalence in Denmark were last estimated in 2010.
In this cross-sectional study, 104,950 individuals aged ≥16 years were randomly sampled for the 2017 Danish Capital Region Health Survey. Responses to questions about headache and use of acute pain medications were linked to demographic registries. MOH was defined as headache ≥15 days/month plus self-report of use of pain medications ≥10 or 15 days/month, in the last three months. Weighted prevalence proportions were calculated.
Among 55,185 respondents, chronic headache prevalence was 3.0% (95% CI: 2.3-3.2) and MOH prevalence was 2.0% (95% CI: 1.8-2.1). Both conditions were more common among females and the middle-aged. Respondents on social welfare or receiving early retirement pensions had the highest prevalences. Among those with chronic headache, 44.7% overused over-the-counter analgesics for headache; paracetamol 41.5%; a combination of different pain relievers 25.3%; ibuprofen 21.9%; opioids 17.0%; combination preparations 14.3%; and triptans 9.1%.
The highest prevalence of chronic headache and MOH was seen among people with low socioeconomic position. Overuse of paracetamol was most common. Reported opioid use was higher than expected. Groups with high prevalence of MOH should be the focus of public health interventions on rational use of OTC and prescription pain medications.
研究慢性头痛和药物过量使用性头痛(MOH)的患病率;确定这些疾病高患病率的群体;并确定慢性头痛受访者中最常用的止痛药物。
丹麦慢性头痛和MOH的患病率上次估计是在2010年。
在这项横断面研究中,从2017年丹麦首都地区健康调查中随机抽取了104,950名年龄≥16岁的个体。关于头痛和急性止痛药物使用问题的回答与人口登记处相关联。MOH被定义为在过去三个月中头痛≥15天/月,加上自我报告使用止痛药物≥10或15天/月。计算加权患病率比例。
在55,185名受访者中,慢性头痛患病率为3.0%(95%CI:2.3 - 3.2),MOH患病率为2.0%(95%CI:1.8 - 2.1)。这两种情况在女性和中年人群中更为常见。领取社会福利或提前退休养老金的受访者患病率最高。在慢性头痛患者中,44.7%过度使用非处方头痛镇痛药;对乙酰氨基酚41.5%;不同止痛药组合25.3%;布洛芬21.9%;阿片类药物17.0%;复方制剂14.3%;曲坦类药物9.1%。
社会经济地位较低人群中慢性头痛和MOH的患病率最高。对乙酰氨基酚的过度使用最为常见。报告的阿片类药物使用高于预期。MOH高患病率群体应成为非处方和处方止痛药物合理使用公共卫生干预的重点。