以孤立性双侧小脑桥脑角肿瘤形式出现的神经结节病：病例报告及文献复习
Neurosarcoidosis Presenting as Isolated Bilateral Cerebellopontine Angle Tumors: Case Report and Review of the Literature.
作者信息
Crawford Fred, Alvi Sameer A, Brahimaj Bledi, Byrne Richard, Kocak Mehmet, Wiet Richard Mark
机构信息
Rush Medical College, Chicago, IL, USA.
Department of Otolaryngology-Head & Neck Surgery, Rush University Medical Center, Chicago, IL, USA.
出版信息
Ear Nose Throat J. 2019 Sep;98(8):NP120-NP124. doi: 10.1177/0145561319860528.
OBJECTIVES
To describe a unique case of isolated bilateral sarcoidosis of the cerebellopontine angle as well as the related imaging in the case. To conduct a literature review of the published articles regarding sarcoidosis of the cerebellopontine angle.
DATA SOURCES
Representative case report from a single institution as well as PubMed and Scopus database searches.
METHODS
In addition to a retrospective review, all published case reports and case series of sarcoidosis involving the cerebellopontine angle from 1960 to July 2018 in the English language were reviewed. Demographic data, presenting symptoms, and outcomes were collected.
RESULTS
We identified 8 total cases with pertinent clinical information that were included.
CONCLUSIONS
Isolated neurosarcoidosis of the cerebellopontine angle is an exceptionally rare phenomenon that, on history and imaging, presents similar to more common retrocochlear pathologies. Surgery may be required in large lesions unresponsive to traditional medical therapy with immunosuppression.
目的
描述一例罕见的孤立性双侧桥小脑角结节病病例及其相关影像学表现。对已发表的关于桥小脑角结节病的文章进行文献综述。
资料来源
来自单一机构的代表性病例报告以及PubMed和Scopus数据库检索。
方法
除了进行回顾性分析外，还对1960年至2018年7月间以英文发表的所有涉及桥小脑角结节病的病例报告和病例系列进行了综述。收集了人口统计学数据、呈现的症状和结局。
结果
我们共纳入了8例具有相关临床信息的病例。
结论
孤立性桥小脑角神经结节病是一种极其罕见的现象，在病史和影像学上与更常见的蜗后病变相似。对于对传统免疫抑制药物治疗无反应的大病灶，可能需要进行手术。
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