Surve Abhidnya, Azad Shorya, Venkatesh Pradeep, Kumar Vinod, Chawla Rohan, Gupta Viney, Vohra Rajpal
Vitreo-retina, Trauma and Uvea Services, Dr. Rajendra Prasad Center for Ophthalmic Sciences, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India.
Vitreo-retina, Trauma and Uvea Services, Dr. Rajendra Prasad Center for Ophthalmic Sciences, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India.
Ophthalmol Retina. 2019 Dec;3(12):1091-1097. doi: 10.1016/j.oret.2019.07.009. Epub 2019 Jul 22.
To study the choroidal vascular pattern in patients with Sturge-Weber syndrome (SWS) using swept-source OCT (SS-OCT).
Prospective comparative observational study.
All patients with SWS with no history of prior treatment for posterior segment pathology were included.
Both eyes of all patients were studied using fundus imaging, SS-OCT, fundus fluorescein angiography (FFA), and indocyanine green angiography (ICG) by 2 independent observers.
The FFA and ICG were screened for any vascular abnormalities. The SS-OCT was evaluated for choroidal changes.
A total of 34 eyes of 17 patients with diagnosed SWS in the age group 9 to 26 years were studied. The FFA and ICG in 7 and 11 patients, respectively, showed some vascular abnormalities. SS-OCT was performed in all patients. The diffuse choroidal hemangioma (DCH) was characterized by loss of the choroidal vascular pattern, increase in the choroidal thickness and loss of visualization of the sclerochoroidal interface. Based on the FFA, ICG, and SS-OCT imaging, there were 3 patients with no DCH, 5 with bilateral DCH, and the remaining 9 patients had unilateral DCH. The detection rate was 50% clinically: 52.94% with FFA, 82.35% with ICG, and 86.36% with SS-OCT. There was substantial agreement between the 2 observers for all 3 investigations.
SS-OCT is a reliable noninvasive imaging modality for early diagnosis and follow-up of DCH over time.
使用扫频源光学相干断层扫描（SS-OCT）研究斯-韦综合征（SWS）患者的脉络膜血管形态。
前瞻性比较观察性研究。
纳入所有既往无后段病变治疗史的SWS患者。
由2名独立观察者使用眼底成像、SS-OCT、眼底荧光血管造影（FFA）和吲哚菁绿血管造影（ICG）对所有患者的双眼进行研究。
筛查FFA和ICG有无血管异常。评估SS-OCT的脉络膜变化。
对年龄在9至26岁的17例确诊SWS患者的34只眼进行了研究。分别有7例和11例患者的FFA和ICG显示出一些血管异常。所有患者均进行了SS-OCT检查。弥漫性脉络膜血管瘤（DCH）的特征为脉络膜血管形态消失、脉络膜厚度增加以及巩膜脉络膜界面可视化消失。根据FFA、ICG和SS-OCT成像，3例患者无DCH，5例为双侧DCH，其余9例为单侧DCH。临床检出率为50%：FFA为52.94%，ICG为82.35%，SS-OCT为86.36%。2名观察者对所有3项检查结果的一致性较高。
SS-OCT是一种可靠的非侵入性成像方法，可用于DCH的早期诊断及长期随访。
Zotero 插件