Institute of Physical Education, Shanghai Normal University, Shanghai 200234, China.
Spare-time Sports School, Yangpu District, Shanghai 200438, China.
J Clin Neurosci. 2019 Dec;70:47-54. doi: 10.1016/j.jocn.2019.08.092. Epub 2019 Sep 13.
OBJECTIVE: This work aimed to assess effects of different exercise intervention on Parkinson's disease (PD) treatment via a network meta-analysis. METHODS: Eligible literatures were retrieved from three databases (PubMed, EMBASE and Cochrane Library) up to March 5, 2019 and screened based on established selection criteria. Afterwards, relevant data was extracted and heterogeneity tests were conducted to select appropriate effect models according to chi-square test and I statistics. Publication bias of included studies was also performed. Finally, the pairwise and network meta-analyses were carried out to evaluate the efficacy of different exercise training on PD management. RESULTS: Overall, 19 studies encompassing 920 PD patients were identified to explore effects of interventions such as dance, Qigong, tango, resistance training (RT), Taichi and yoga on PD in terms of six indicators including six-minute walk, gait velocity, UPDRS III, PD questionnaire-39 (PDQ-39), timed up and go (TUG) and Berg balance test (BBT). The direct meta-analysis revealed that RT and dance altered the gait velocity and PDR-39 indicator of PD patients. And there was a statistical difference in RT and Tango regarding UPDRS III. Besides, significant differences were also detected among multiple comparisons based on TUG and BBT, containing RT vs control, Tai Chi vs control and Tango vs control for TUG, and dance vs control for BBT. Finally, results of network meta-analysis implied that tango was a good exercise for PD patients according to six different outcome measures. CONCLUSION: Tango was an optimal and effective option for improving functional mobility of PD patients.
目的:本研究旨在通过网络荟萃分析评估不同运动干预对帕金森病(PD)治疗的效果。
方法:检索 2019 年 3 月 5 日前在三个数据库(PubMed、EMBASE 和 Cochrane Library)中符合条件的文献,并根据既定的选择标准进行筛选。然后,提取相关数据,并进行异质性检验,根据卡方检验和 I 统计量选择合适的效应模型。还对纳入研究的发表偏倚进行了分析。最后,进行了两两和网络荟萃分析,以评估不同运动训练对 PD 管理的疗效。
结果:总共确定了 19 项研究,共纳入 920 名 PD 患者,以探讨舞蹈、气功、探戈、抗阻训练(RT)、太极和瑜伽等干预措施对 PD 的六项指标(包括 6 分钟步行、步态速度、UPDRS III、PD 问卷-39(PDQ-39)、起立和行走时间(TUG)和伯格平衡测试(BBT))的影响。直接荟萃分析显示,RT 和舞蹈改变了 PD 患者的步态速度和 PDQ-39 指标。而在 UPDRS III 方面,RT 和探戈有统计学差异。此外,基于 TUG 和 BBT 的多项比较也存在显著差异,包括 RT 与对照组、太极与对照组和探戈与对照组的 TUG,以及舞蹈与对照组的 BBT。最后,网络荟萃分析的结果表明,探戈是一种改善 PD 患者功能移动能力的较好运动方式。
结论:探戈是改善 PD 患者功能移动能力的一种有效方法。
J Clin Neurosci. 2019-9-13
Cochrane Database Syst Rev. 2024-4-8
Cochrane Database Syst Rev. 2012-7-11
Cochrane Database Syst Rev. 2013-9-10
Cochrane Database Syst Rev. 2012-8-15
Int J Environ Res Public Health. 2019-12-18
Cochrane Database Syst Rev. 2023-1-5
J Back Musculoskelet Rehabil. 2024
Medicine (Baltimore). 2025-1-24
Front Public Health. 2024-12-16
Cochrane Database Syst Rev. 2024-4-8