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运动干预对帕金森病的影响:贝叶斯网络荟萃分析。

The effects of exercise interventions on Parkinson's disease: A Bayesian network meta-analysis.

机构信息

Institute of Physical Education, Shanghai Normal University, Shanghai 200234, China.

Spare-time Sports School, Yangpu District, Shanghai 200438, China.

出版信息

J Clin Neurosci. 2019 Dec;70:47-54. doi: 10.1016/j.jocn.2019.08.092. Epub 2019 Sep 13.


DOI:10.1016/j.jocn.2019.08.092
PMID:31526677
Abstract

OBJECTIVE: This work aimed to assess effects of different exercise intervention on Parkinson's disease (PD) treatment via a network meta-analysis. METHODS: Eligible literatures were retrieved from three databases (PubMed, EMBASE and Cochrane Library) up to March 5, 2019 and screened based on established selection criteria. Afterwards, relevant data was extracted and heterogeneity tests were conducted to select appropriate effect models according to chi-square test and I statistics. Publication bias of included studies was also performed. Finally, the pairwise and network meta-analyses were carried out to evaluate the efficacy of different exercise training on PD management. RESULTS: Overall, 19 studies encompassing 920 PD patients were identified to explore effects of interventions such as dance, Qigong, tango, resistance training (RT), Taichi and yoga on PD in terms of six indicators including six-minute walk, gait velocity, UPDRS III, PD questionnaire-39 (PDQ-39), timed up and go (TUG) and Berg balance test (BBT). The direct meta-analysis revealed that RT and dance altered the gait velocity and PDR-39 indicator of PD patients. And there was a statistical difference in RT and Tango regarding UPDRS III. Besides, significant differences were also detected among multiple comparisons based on TUG and BBT, containing RT vs control, Tai Chi vs control and Tango vs control for TUG, and dance vs control for BBT. Finally, results of network meta-analysis implied that tango was a good exercise for PD patients according to six different outcome measures. CONCLUSION: Tango was an optimal and effective option for improving functional mobility of PD patients.

摘要

目的:本研究旨在通过网络荟萃分析评估不同运动干预对帕金森病(PD)治疗的效果。

方法:检索 2019 年 3 月 5 日前在三个数据库(PubMed、EMBASE 和 Cochrane Library)中符合条件的文献,并根据既定的选择标准进行筛选。然后,提取相关数据,并进行异质性检验,根据卡方检验和 I 统计量选择合适的效应模型。还对纳入研究的发表偏倚进行了分析。最后,进行了两两和网络荟萃分析,以评估不同运动训练对 PD 管理的疗效。

结果:总共确定了 19 项研究,共纳入 920 名 PD 患者,以探讨舞蹈、气功、探戈、抗阻训练(RT)、太极和瑜伽等干预措施对 PD 的六项指标(包括 6 分钟步行、步态速度、UPDRS III、PD 问卷-39(PDQ-39)、起立和行走时间(TUG)和伯格平衡测试(BBT))的影响。直接荟萃分析显示,RT 和舞蹈改变了 PD 患者的步态速度和 PDQ-39 指标。而在 UPDRS III 方面,RT 和探戈有统计学差异。此外,基于 TUG 和 BBT 的多项比较也存在显著差异,包括 RT 与对照组、太极与对照组和探戈与对照组的 TUG,以及舞蹈与对照组的 BBT。最后,网络荟萃分析的结果表明,探戈是一种改善 PD 患者功能移动能力的较好运动方式。

结论:探戈是改善 PD 患者功能移动能力的一种有效方法。

相似文献

[1]
The effects of exercise interventions on Parkinson's disease: A Bayesian network meta-analysis.

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[2]
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[3]
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[4]
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[5]
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[6]
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[7]
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[8]
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[9]
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[10]
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引用本文的文献

[1]
Effects of remote Baduanjin Qigong intervention on quality of life and physical function in patients with mild to moderate Parkinson's disease: a protocol of randomized controlled trial.

Front Neurol. 2025-8-6

[2]
Patient-centered brain transcriptomic and multimodal imaging determinants of clinical progression, physical activity, and treatment needs in Parkinson's disease.

NPJ Parkinsons Dis. 2025-2-15

[3]
Factors associated with higher caregiver burden among informal caregivers of Parkinson's disease: A systematic review.

Medicine (Baltimore). 2025-1-24

[4]
The effects of dance interventions on reducing the risk of falls in older adults: a network meta-analysis.

Front Public Health. 2024-12-16

[5]
Quality assessment and umbrella review of systematic reviews about dance for people with Parkinson's disease.

PLoS One. 2024-12-31

[6]
Sensorimotor functioning changes in response to global exercise versus handwriting upper limb exercise training in Parkinson's disease, results from a phase II randomised controlled trial.

PLoS One. 2024

[7]
Non-pharmacological therapies for treating non-motor symptoms in patients with Parkinson's disease: a systematic review and meta-analysis.

Front Aging Neurosci. 2024-4-26

[8]
Physical exercise for people with Parkinson's disease: a systematic review and network meta-analysis.

Cochrane Database Syst Rev. 2024-4-8

[9]
Effects of aerobic exercise on children's executive function and academic performance: A systematic review and meta-analysis.

Heliyon. 2024-3-27

[10]
Comparative efficacy of 24 exercise types on postural instability in adults with Parkinson's disease: a systematic review and network meta-analysis.

BMC Geriatr. 2023-8-28

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