一种用于在无症状HBsAg血清阳性个体中识别早期肝细胞癌的液体活检检测方法。
A liquid biopsy assay for identifying early-stage hepatocellular carcinoma in asymptomatic HBsAg-seropositive individuals.
作者信息
Qu Chunfeng, Jiao Yuchen, Wang Yuting
机构信息
State Key Laboratory of Molecular Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
出版信息
Mol Cell Oncol. 2019 May 28;6(5):e1614419. doi: 10.1080/23723556.2019.1614419. eCollection 2019.
Biannual screening of hepatocellular carcinoma (HCC) by ultrasonography and serum α-fetoprotein has been proposed to the HBsAg-seropositive individuals. The widespread application to all of them was restricted due to limited acceptability of resource and anxiety-producing procedures. We recently developed a novel liquid biopsy assay to identify HCC cases in asymptomatic HBsAg-positive individuals.
已建议对乙肝表面抗原血清阳性个体每半年进行一次超声检查和血清甲胎蛋白检测以筛查肝细胞癌（HCC）。由于资源可接受性有限以及检查程序会引发焦虑，因此无法将该检查广泛应用于所有此类个体。我们最近开发了一种新型液体活检检测方法，用于识别无症状乙肝表面抗原阳性个体中的肝癌病例。
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