Tupoleva T A, Ignatova E N, Gulyaeva A A, Ovchinnikova E N, Tikhomirov D S, Abakarov R R, Romanova T Yu, Yaroslavtseva N G, Koroleva O M, Garanzha T A, Filatov F P, Gaponova T V, Savchenko V G
The hematological research center of Minzdrav of Russia, 125167, Moscow, Russia.
Klin Lab Diagn. 2016;61(5):311-316. doi: 10.18821/0869-2084-2016-61-5-311-316.
Despite application of decreed modes of laboratory analysis of components of donors' blood, the risk of infection of recipients with hepatitis B virus continues to be actual. The isolated identification of HBsAg provides no control of all categories of persons infected with hepatitis B virus. The analysis of presence of antibodies to nuclear antigen of hepatitis B virus that are the first out of antiviral ones and are preserved for life, is an expedient technique of screening testing of donor's blood that permits implementing an additional selection of donors. During March 2014 - March 2015, cohort of regular anti-hepatitis B virus negative donors of blood and its components. The testing of blood samples for anti-hepatitis B virus can be recommended as a routine test increasing viral safety of blood transfusions for patients with diseases of blood system.
尽管采用了规定的供体血液成分实验室分析模式，但受血者感染乙型肝炎病毒的风险仍然存在。仅通过分离鉴定乙肝表面抗原（HBsAg）并不能对所有感染乙型肝炎病毒的人群进行管控。分析乙肝病毒核抗原抗体的存在情况是一种合适的供体血液筛查检测技术，该抗体是最早出现的抗病毒抗体且终身存在，它能实现对供体的额外筛选。在2014年3月至2015年3月期间，对定期献血且乙肝病毒检测呈阴性的供体及其血液成分进行了队列研究。对于血液系统疾病患者，将血液样本检测乙肝病毒抗体作为一项常规检测推荐使用，可提高输血的病毒安全性。
