甲状旁腺功能亢进症中与高钙血症危象相关的急性胰腺炎：一例报告。
Acute pancreatitis connected with hypercalcemia crisis in hyperparathyroidism: A case report.
作者信息
Ma Yi-Bo, Hu Jun, Duan Yun-Fei
机构信息
Department of B-mode Ultrasound, The First People's Hospital of Changzhou, Changzhou 213003, Jiangsu Province, China.
Department of Hepatobiliary Surgery, The First People's Hospital of Changzhou, Changzhou 213003, Jiangsu Province, China.
出版信息
World J Clin Cases. 2019 Aug 26;7(16):2367-2373. doi: 10.12998/wjcc.v7.i16.2367.
BACKGROUND
The association between primary hyperparathyroidism (PHPT) and acute pancreatitis is rarely reported. Here we describe the process of acute pancreatitis-mediated PHPT induced by hypercalcemia in a male patient. Hypercalcemia induced by undiagnosed PHPT may be the causative factor in recurrent acute pancreatitis.
CASE SUMMARY
We report a case of hypercalcemia-induced acute pancreatitis caused by a functioning parathyroid adenoma in a 57-year-old man. The patient initially experienced a series of continuous gastrointestinal symptoms including abdominal distension, abdominal pain, nausea, vomiting, electrolyte disturbance, renal dysfunction, and acute pancreatitis. Due to prolonged hypercalcemia, the patient subsequently underwent surgical resection of the parathyroid adenoma. Two weeks after surgery, his serum calcium, amylase, and lipase concentrations were normal. The patient had a good recovery after a series of other relevant therapies.
CONCLUSION
Acute pancreatitis as the first presentation is a rare clinical symptom caused by PHPT-induced hypercalcemia.
背景
原发性甲状旁腺功能亢进症（PHPT）与急性胰腺炎之间的关联鲜有报道。在此，我们描述了一名男性患者因高钙血症引发的急性胰腺炎介导的PHPT过程。未诊断出的PHPT所导致的高钙血症可能是复发性急性胰腺炎的致病因素。
病例摘要
我们报告一例由功能性甲状旁腺腺瘤引起的高钙血症性急性胰腺炎，患者为一名57岁男性。患者最初出现一系列持续的胃肠道症状，包括腹胀、腹痛、恶心、呕吐、电解质紊乱、肾功能不全和急性胰腺炎。由于长期高钙血症，患者随后接受了甲状旁腺腺瘤手术切除。术后两周，他的血清钙、淀粉酶和脂肪酶浓度恢复正常。经过一系列其他相关治疗后，患者恢复良好。
结论
急性胰腺炎作为首发症状是由PHPT引起的高钙血症导致的一种罕见临床症状。
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