Alghadir Ahmad H, Gabr Sami A, Rizk Ashraf A
. Rehabilitation Research Chair, College of Applied Medical Sciences, King Saud University, Riyadh, KSA.
. Department of Biomechanics & Motor Behavior, College of Sport Sciences & Physical Activity, King Saud University, Riyadh, KSA.
Rev Assoc Med Bras (1992). 2019 Sep 12;65(8):1061-1066. doi: 10.1590/1806-9282.65.8.1061.
The aim of this study was to determine the potential association of foot pain and plasmatic adipocytes as physiological biomarkers of childhood obesity with the incidence of flatfoot in a cohort of Egyptian school children aged 6 -12 years.
A total of 550 Egyptian schoolchildren (220 boys and 330 girls) aged 6-12 years were randomly invited to participate in this descriptive survey analysis. For all children, we assessed the diagnosis and severity of flatfoot as well as plasma adipocytes, as well as adiponectin, leptin, resistin, IL-6, and TNF-α, using the Dennis method and immunoassay techniques respectively. Foot pain was assessed by using a standard VAS of 100 mm and Faces Pain Scale, respectively.
Flat foot was predicted in 30.4% of school-age children, most of them showed a higher frequency of overweight (33.3%) and obesity (62.5%). Boys showed higher ranges of flat foot than girls. Foot pain significantly correlated with flat foot and obesity among the studied populations. In overweight-obese children, plasmatic adipocyte variables, as well as adiponectin, leptin, resistin, IL-6, TNF-α showed significant correlations with foot stance, especially in boys. Also, the studied adipocyte variables along with BMI, age, gender explained about~65% of the variance of flatfoot with pain among our school-age students.
Foot pain showed an association with flat foot and childhood obesity in 30.4% of school-age students (6-12 years). Foot pain was shown to correlate positively with the incidence of flat foot and changes in adiposity markers, as well as adiponectin, leptin, resistin, Il-6, TNF-α.
本研究旨在确定6至12岁埃及学龄儿童队列中，足痛和作为儿童肥胖生理生物标志物的血浆脂肪细胞与扁平足发病率之间的潜在关联。
随机邀请了550名6至12岁的埃及学龄儿童（220名男孩和330名女孩）参与这项描述性调查分析。对于所有儿童，我们分别使用丹尼斯方法和免疫测定技术评估扁平足的诊断和严重程度，以及血浆脂肪细胞、脂联素、瘦素、抵抗素、白细胞介素-6和肿瘤坏死因子-α。分别使用100毫米标准视觉模拟评分法和面部疼痛量表评估足痛。
30.4%的学龄儿童被预测为扁平足，其中大多数超重（33.3%）和肥胖（62.5%）的发生率较高。男孩的扁平足发生率高于女孩。在所研究的人群中，足痛与扁平足和肥胖显著相关。在超重肥胖儿童中，血浆脂肪细胞变量以及脂联素、瘦素、抵抗素、白细胞介素-6、肿瘤坏死因子-α与足部姿势显著相关，尤其是在男孩中。此外，所研究的脂肪细胞变量以及体重指数、年龄、性别解释了我们学龄学生中伴有疼痛的扁平足约65%的变异。
在30.4%的6至12岁学龄儿童中，足痛与扁平足和儿童肥胖有关。足痛与扁平足的发生率以及肥胖标志物、脂联素、瘦素、抵抗素、白细胞介素-6、肿瘤坏死因子-α的变化呈正相关。
