Histopathology Section, Department of Pathology and Laboratory Medicine, Aga Khan University Hospital, Karachi, Pakistan.
Breast J. 2020 Feb;26(2):211-215. doi: 10.1111/tbj.13521. Epub 2019 Sep 18.
Solid papillary carcinoma (SPC) is an uncommon breast tumor whose prognosis depends on invasive component. We studied clinicopathological features of SPC by reviewing 65 cases. Invasive component was seen in 75.4% cases. Almost all tumors with grade III nuclei had invasive component. Mean patients' age of invasive tumors was significantly higher than that of non-invasive tumors (P = .036). All patients were alive and disease free except for a single patient who developed distant metastasis and died of disease. SPC have excellent clinical course. Careful search for invasive component is mandatory, especially in tumors with older patient's age and higher nuclear grade.
实性乳头状癌（SPC）是一种罕见的乳腺肿瘤，其预后取决于浸润性成分。我们通过复习 65 例病例研究了 SPC 的临床病理特征。浸润性成分见于 75.4%的病例。几乎所有核级为 III 级的肿瘤均有浸润性成分。浸润性肿瘤患者的平均年龄明显高于非浸润性肿瘤（P =.036）。除 1 例发生远处转移并死于疾病的患者外，所有患者均存活且无疾病。SPC 具有良好的临床病程。必须仔细寻找浸润性成分，特别是在年龄较大和核级较高的肿瘤中。
